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Morphometric model for pulmonary diffusing capacity I. Membrane diffusing capacity

Respiration Physiology, 1993
The pulmonary diffusing capacity is related to the quantitative design characteristics of the pulmonary gas exchanger. The current model for estimating DLO2 from morphometric data breaks the diffusion path for O2 into four steps, three of which represent the membrane part of DLO2.
R. Vock   +6 more
openaire   +3 more sources

Lung Diffusing Capacity [PDF]

open access: possible, 2005
Transfer of oxygen and carbon dioxide over the alveolocapillary membrane is the main function of the lungs and can be measured by the diffusing capacity for carbon monoxide (CO). CO has a high affinity for hemoglobin and is absent in pulmonary capillary blood.
J.C. de Jongste   +2 more
openaire   +1 more source

Standardized single breath normal values for carbon monoxide diffusing capacity.

American Review of Respiratory Disease, 2015
Prediction equations for DLCO and diffusing capacity per unit of lung volume (DL/VA) were generated from 245 normal subjects (122 women and 123 men) using a standardized technique for measuring DLCO. Measurements were made at an altitude of 1,400 meters.
R. Crapo, A. Morris
semanticscholar   +1 more source

Carbon Monoxide Diffusing Capacity

Clinics in Chest Medicine, 1989
Before measuring single-breath DLCO it is important to: (1) standardize carefully test technique and computation using current ATS guidelines; (2) confirm that computerized systems correctly perform the calculations; and (3) confirm that the reference values selected are consistent with the data produced by the device in the laboratory by comparing ...
Robert E. Forster, Robert O. Crapo
openaire   +3 more sources

Pulmonary diffusing capacity of athletes

Journal of Applied Physiology, 1963
Champion swimmers have been found to have significantly higher steady-state pulmonary diffusing capacities than those measured in normal subjects of comparable age at the same exercise level. Nonactive and moderately active normal subjects, swimmers of average ability, long distance runners, and older ex-athletes were found to show no significant ...
L. G. Bentivoglio   +4 more
openaire   +3 more sources

Diffusing capacity, membrane diffusing capacity, capillary blood volume, pulmonary tissue volume, and cardiac output measured by a rebreathing technique.

American Review of Respiratory Disease, 2015
A rebreathing method for estimating diffusing capacity, membrane diffusing capacity, pulmonary capillary blood volume, pulmonary capillary blood flow, and pulmonary tissue volume consists of rebreathing into a bag for 15 sec while acetylene, (18O)-carbon
M. Sackner   +4 more
semanticscholar   +1 more source

Diffusing Capacity

Clinical Reviews in Allergy & Immunology, 2009
The diffusing capacity for carbon monoxide (DL(CO)) is a commonly performed and clinically useful pulmonary function test that provides a quantitative measure of gas transfer in the lungs. It is valuable for evaluating and managing patients with a wide variety of pulmonary disorders, especially patients with interstitial lung disease, pulmonary ...
openaire   +3 more sources

The Reliability of the Pulmonary Diffusing Capacity Determination

Scandinavian Journal of Clinical and Laboratory Investigation, 1962
The test-retest reliability of the ten second breath-holding method for the determination of pulmonary diffusing capacity of carbon monoxide was studied in a series of 151 men and women, including patients, normal subjects and athletes.The mean and standard deviation of the DLCO was 28.2 ± 10.09 ml × min−1 × mmHg−1.
M. J. Karvonen   +2 more
openaire   +3 more sources

Overestimation of the single-breath carbon monoxide diffusing capacity in patients with air-flow obstruction.

American Review of Respiratory Disease, 2015
It has been previously shown that conventional methods of measuring the single-breath diffusing capacity of the lung for carbon monoxide (DLCOsb) overestimate diffusion in normal subjects when the expiratory flow rate is reduced, when the collection of ...
B. Graham, J. Mink, D. Cotton
semanticscholar   +1 more source

A simplified morphometric method for estimating diffusing capacity in normal and emphysematous human lungs.

American Review of Respiratory Disease, 2015
A simple method was developed for estimating pulmonary diffusing capacity by morphometry using light microscopic preparations of normal and diseased human lungs. It should be particularly useful in studying emphysematous lungs obtained at autopsy in view
E. Weibel
semanticscholar   +1 more source

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