ABSTRACT Multimodal chromatography has emerged as a powerful tool for the purification of monoclonal antibodies (mAbs) and their derivatives—including antibody fragments (Fabs), Fc‐fusions, bispecific (BsAb), and antibody–drug conjugates (ADCs)—offering enhanced selectivity through the integration of ionic, hydrophobic, hydrogen‐bonding, and π–π ...
Amin Javidanbardan +4 more
wiley +1 more source
SOR-Based numerical modeling of hybrid nanofluid flow over a rotating disk with magneto-nonlinear radiation and arrhenius activation energy considering shape factors. [PDF]
Ahmad A +5 more
europepmc +1 more source
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal +5 more
wiley +1 more source
An experimental study and mathematical formulation for hydrogen diffusion in water. [PDF]
Ahmadpour S +3 more
europepmc +1 more source
Metasurface Enhanced Photothermal Cement Foam for Robust and High‐Throughput Seawater Desalination
Schematic of 3D metasurface‐enhanced cement foam for robust and high‐throughput seawater desalination. This study presents a cement‐based solar evaporator (CSE) fabricated in one step via viscoelastic lithography with simple negative pressure. In addition to boosting solar‐to‐vapor conversion efficiency via excellent light‐harvesting capacity, the ...
Jianjun Guo +4 more
wiley +1 more source
Integrating computational fluid dynamics into organ-on-chip systems: a glioblastoma-centred design and validation framework. [PDF]
Taleban H +6 more
europepmc +1 more source
An expandable‐thickness graphene block (GPB) with high thermal conductivity synthesized through multiscale blending and multistage pressure induction (MBP) achieves a record thickness of 12.1 mm, which is more than 10 times that of existing graphene materials. The maximum thermal diffusion ability of GPB‐MBP reaches 6.3 W/K, which offers a new approach
Liyu Zhang +9 more
wiley +1 more source
Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing. [PDF]
Srisuma P, Chen G, Braatz RD.
europepmc +1 more source
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Numerical investigation of MHD stratified flow over an inclined cylinder with Brownian motion, thermophoresis and waste discharge concentration effects. [PDF]
Rafique K +5 more
europepmc +1 more source

