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Diffusion MRI in multiple sclerosis

Neurology, 2005
Diffusion imaging is a quantitative, MR-based technique potentially useful for the study of multiple sclerosis (MS), due to its increased pathologic specificity over conventional MRI and its ability to assess in vivo the presence of tissue damage occurring outside T2-visible lesions, i.e., in the so-called normal-appearing white and gray matter.
Rovaris M   +6 more
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Diffusion of water in tissues and MRI

Magnetic Resonance in Medicine, 1991
AbstractThe purpose of this paper is to present an overview of the diffusive behavior of water in biological tissues. The analysis shows that obstructive barriers would have to occupy very large volume fractions in order to account for the reduction in the diffusion coefficient (D) observed in biological systems.
C F, Hazlewood, H E, Rorschach, C, Lin
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Diffusion-MRI in neurodegenerative disorders

Magnetic Resonance Imaging, 2015
The ability to image the whole brain through ever more subtle and specific methods/contrasts has come to play a key role in understanding the basis of brain abnormalities in several diseases. In magnetic resonance imaging (MRI), "diffusion" (i.e. the random, thermally-induced displacements of water molecules over time) represents an extraordinarily ...
Joseph Goveas a   +13 more
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MRI and Diffusion MRI in nonparaneoplastic limbic encephalitis

Computerized Medical Imaging and Graphics, 2002
This paper reports an 65-year-old woman with nonparaneoplastic limbic encephalitis. On MRI and diffusion MRI, diffuse and symmetrical, bilateral high-signal lesions were evident in the medial temporal lobes. The affected areas were hyperintense on b= 1000 s/mm(2) (heavily diffusion-weighted or true diffusion) images, a pattern similar to cytotoxic ...
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ADEM: diffusion MRI findings

European Journal of Radiology Extra, 2003
Abstract Acute disseminated encephalomyelitis (ADEM) usually reveals patchy demyelinated lesions with high signal on T2-weighted sequences. Diffusion MRI in a 10-year-old patient with ADEM demonstrated two distinct lesion patterns occurring simultaneously in the cerebral white matter. These were a restricted diffusion pattern (high-signal on b =1000
Sener R.N.   +3 more
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Fundamentals of diffusion MRI physics

NMR in Biomedicine, 2017
Diffusion MRI is commonly considered the “engine” for probing the cellular structure of living biological tissues. The difficulty of this task is threefold. First, in structurally heterogeneous media, diffusion is related to structure in quite a complicated way.
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Diffusion‐weighted MRI of fatty liver

Journal of Magnetic Resonance Imaging, 2011
AbstractPurpose:To investigate the effect of fat infiltration on the apparent diffusion coefficient (ADC) of liver, and assess the relationship between ADC and hepatic fat fraction (HFF).Materials and Methods:MRI scans of 120 consecutive patients were included in this retrospective study. Of these, 42 patients were included in the fatty liver group and
POYRAZ, AHMET KÜRŞAD   +3 more
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Diffusion MRI findings in phenylketonuria

European Radiology, 2003
Two patients with phenylketonuria were studied who were under dietary control since infancy, and who were mentally normal. Diffusion MRI was obtained using a spin-echo, echo-planar sequence with a gradient strength of 30 mT/m at 1.5 T. A trace sequence (TR=5700 ms, and TE=139 ms) was used, acquired in 22 s.
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Diffusion MRI Outside the Brain

2019
This manuscript provides an overview of recent developments in Diffusion-Weighted Imaging (DWI) outside the brain, focusing on liver, breast, prostate, muskuloskeletal (MSK) and cardiac applications. A general introduction to cross-cutting acquisition and image processing challenges is first provided. These often include short \(T_2\) relaxation times,
Rita G. Nunes   +4 more
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Combining Functional and Diffusion Tensor MRI

Annals of the New York Academy of Sciences, 2005
Functional magnetic resonance imaging (fMRI) of the perceptual, motor, and cognitive capacities in humans is of increasing importance for basic and clinical neurosciences. The explanatory power of current fMRI techniques could be greatly expanded, however, if the pattern of the neuronal connections between the active cortical areas
Kim, DS Kim, Dae-Shik, Kim, M
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