Results 31 to 40 of about 393,171 (263)

Using First-Passage Times to Analyze Tumor Growth Delay

open access: yesMathematics, 2021
A central aspect of in vivo experiments with anticancer therapies is the comparison of the effect of different therapies, or doses of the same therapeutic agent, on tumor growth.
Patricia Román-Román   +3 more
doaj   +1 more source

Driving Factors for Opinion Diffusion Behavior in Consumers on Online Social Networks: A Study of Network Characteristics

open access: yesIEEE Access, 2019
Online consumer social networks have become an important marketing channel for product-related information diffusion in the technological landscape. This paper aims to identify the factors that drive opinion diffusion behavior in consumers on online ...
Peng Shao, Heng Chen
doaj   +1 more source

On the Transformation of Diffusion Processes into the Wiener Process [PDF]

open access: yesSIAM Journal on Applied Mathematics, 1980
Necessary and sufficient conditions are given for transforming (constructively) a one-dimensional diffusion process described by a Kolmogorov equation into the Wiener process. These conditions are shown to be equivalent to invariance of a parabolic partial differential equation under a six-parameter Lie group of point transformations.
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Original Music Album Diffusion Sustainability in Social Network-Based Communities: A Network Embedded Perspective

open access: yesIEEE Access, 2020
An original music album is a collection of music created by an online musician, and is a special form of User Generated Content. This paper aims to identify the factors that drive original music album diffusion in online music community.
Genqiang Li, Renjing Liu
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A Note on Estimation of Multi-Sigmoidal Gompertz Functions with Random Noise

open access: yesMathematics, 2019
The behaviour of many dynamic real phenomena shows different phases, with each one following a sigmoidal type pattern. This requires studying sigmoidal curves with more than one inflection point. In this work, a diffusion process is introduced whose mean
Patricia Román-Román   +2 more
doaj   +1 more source

Reduced Markovian Descriptions of Brownian Dynamics: Toward an Exact Theory

open access: yesFrontiers in Physics, 2022
We outline a reduction scheme for a class of Brownian dynamics which leads to meaningful corrections to the Smoluchowski equation in the overdamped regime.
Matteo Colangeli, Adrian Muntean
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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