Diffusion-weighted MRI in head and neck radiology: applications in oncology
Extracranial application of diffusion-weighted magnetic resonance imaging (MRI) has gained increasing importance in recent years. As a result of technical advances, this new non-invasive functional technique has also been applied in head and neck ...
Thoeny,
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Stroke penumbra defined by an MRI-based oxygen challenge technique: 1. validation using [14C]2-deoxyglucose autoradiography [PDF]
Accurate identification of ischemic penumbra will improve stroke patient selection for reperfusion therapies and clinical trials. Current magnetic resonance imaging (MRI) techniques have limitations and lack validation.
Robertson, Craig A +23 more
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ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
The Desmoteplase In Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase [PDF]
<p><b>Background and Purpose:</b> Most acute ischemic stroke patients arrive after the 3-hour time window for recombinant tissue plasminogen activator (rtPA) administration.
Fischer, M. +9 more
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T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Reliable identification of the auditory thalamus using multi-modal structural analyses. [PDF]
The medial geniculate body (MGB) of the thalamus is a key component of the auditory system. It is involved in relaying and transforming auditory information to the cortex and in top-down modulation of processing in the midbrain, brainstem, and ear ...
Johansen-Berg, Heidi +29 more
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ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Role of Magnetic Resonance Imaging in Diagnosis of Endometrial and Cervical Malignancies [PDF]
Background: Endometrial and cervical cancers are common worldwide for gynecological cancers. MRI has been shown to be the most accurate non-invasive technique for endometrial and cervical cancer staging, which is necessary to make the right medical ...
Hosam Almassry +3 more
doaj +1 more source
The use of conventional and advanced magnetic resonance techniques in the assessment of primary brain tumours [PDF]
The aim of the work described in this thesis was to investigate the value of conventional, perfusion- and diffusion-weighted magnetic resonance imaging (MRI) in patients with histology-proven low-grade gliomas (LGG), and the potential role of these ...
Caseiras, G.D.B.
core
Impact of image enhancement on the radiomics stability of diffusion-weighted MRI images of cervical cancer [PDF]
The diffusion-weighted imaging (DWI) technique is known for its capability to differentiate the diffusion of water molecules between cancerous and non-cancerous cervix tissues, which enhances the accuracy of detection.
Ramli, Zarina +4 more
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