Results 51 to 60 of about 244,982 (129)

Inhibition of DEF‐p65 Interactions as a Potential Avenue to Suppress Tumor Growth in Pancreatic Cancer

open access: yesAdvanced Science, Volume 11, Issue 28, July 24, 2024.
The study identifies the digestive organ expansion factor (DEF) as a key player in pancreatic cancer, correlating high DEF expression with poor patient survival. DEF interacts with p65, preventing it from ubiquitination‐induced degradation and promoting tumor cell survival.
Sicong Huang   +11 more
wiley   +1 more source

Acceleration of catalyst discovery with easy, fast, and reproducible computational alchemy

open access: yesInternational Journal of Quantum Chemistry, 2020
The expense of quantum chemistry calculations significantly hinders the search for novel catalysts. Here, we provide a tutorial for using an easy and highly cost-efficient calculation scheme called alchemical perturbation density functional theory (APDFT)
Charles D Griego, J. Kitchin, J. Keith
semanticscholar   +1 more source

The Transition from Alchemical to Modern Chemical Symbolism: from Bergman and Guiton de Morveau to Hassenfratz and Adet, Higgins, Richter, Dalton, and Berzelius

open access: yesChemPlusChem, Volume 89, Issue 7, July 2024.
The alchemical symbols for metals, acids, bases and salts were still in everyday use in much of the 18th century. The modern notation, which we use today, is due to Berzelius, but the transition was long and arduous and took place between ca. 1775 and 1820 roughly simultaneously with but distinct from the Chemical Revolution.
Curt Wentrup
wiley   +1 more source

Assessment, feedback and the alchemy of learning

open access: yesMedical Education, 2018
Models of sound assessment practices increasingly emphasise assessment's formative role. As a result, assessment must not only support sound judgements about learner competence, but also generate meaningful feedback to guide learning.
C. Watling, S. Ginsburg
semanticscholar   +1 more source

Nurturing longevity through natural compounds: Where do we stand, and where do we go?

open access: yesFood Frontiers, Volume 5, Issue 2, Page 267-310, March 2024.
Abstract The revolution in aging research through the past decade has driven the progress in interventions that promote longevity. Dissection of the “old” hallmarks of aging has provided solid data for the definition of at least three “new” ones, opening avenues for the development of novel hallmark‐targeted pro‐longevity approaches.
Monika N. Todorova   +3 more
wiley   +1 more source

A review of anaerobic digestion systems for biodegradable waste: Configurations, operating parameters, and current trends

open access: yesEnvironmental Engineering Research, 2019
With benefits to the human health, environment, economy, and energy, anaerobic digestion (AD) systems have attracted remarkable attention within the scientific community.
D. Van   +4 more
semanticscholar   +1 more source

Large scale relative protein ligand binding affinities using non-equilibrium alchemy

open access: yesChemical Science, 2019
Ligand binding affinity calculations based on molecular dynamics (MD) simulations and non-physical (alchemical) thermodynamic cycles have shown great promise for structure-based drug design.
Vytautas Gapsys   +6 more
semanticscholar   +1 more source

Division of labor in honey bee gut microbiota for plant polysaccharide digestion

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance Honey bees and other social bees harbor specialized gut microbiota dominated by 5 coevolved bacterial clusters. Bees eat pollen, which contains diverse polysaccharides, energy-rich substrates potentially digested by gut bacteria ...
Hao Zheng   +8 more
semanticscholar   +1 more source

Biomethane Production From Lignocellulose: Biomass Recalcitrance and Its Impacts on Anaerobic Digestion

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Anaerobic digestion using lignocellulosic material as the substrate is a cost-effective strategy for biomethane production, which provides great potential to convert biomass into renewable energy.
N. Xu   +7 more
semanticscholar   +1 more source

Design of Innovative Biocompatible Cellulose Nanostructures for the Delivery and Sustained Release of Curcumin. [PDF]

open access: yesPharmaceutics, 2023
Casanova F   +8 more
europepmc   +1 more source

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