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Conditional Cell Reprogramming in Modeling Digestive System Diseases [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Digestive diseases have become an important source of morbidity and mortality. The considerable financial and health burdens caused by digestive diseases confirm the importance of extensive research to better understand and treat these diseases.
Ruihua Zhao   +7 more
doaj   +7 more sources

Burden of digestive system diseases in China and its provinces during 1990–2019: Results of the 2019 Global Disease Burden Study [PDF]

open access: yesChinese Medical Journal
. Background:. Evaluating the impact of digestive system diseases is vital for devising effective prevention strategies. However, comprehensive reports on the burden of digestive system diseases in China are lacking.
Zhiyuan Cheng   +11 more
doaj   +3 more sources

Lactobacillus reuteri in digestive system diseases: focus on clinical trials and mechanisms. [PDF]

open access: yesFront Cell Infect Microbiol, 2023
Objectives Digestive system diseases have evolved into a growing global burden without sufficient therapeutic measures. Lactobacillus reuteri (L.
Peng Y   +5 more
europepmc   +2 more sources

Applications and Prospects of Artificial Intelligence-Assisted Endoscopic Ultrasound in Digestive System Diseases. [PDF]

open access: yesDiagnostics (Basel), 2023
Endoscopic ultrasound (EUS) has emerged as a widely utilized tool in the diagnosis of digestive diseases. In recent years, the potential of artificial intelligence (AI) in healthcare has been gradually recognized, and its superiority in the field of EUS ...
Huang J, Fan X, Liu W.
europepmc   +2 more sources

Diet as a Source of Acrolein: Molecular Basis of Aldehyde Biological Activity in Diabetes and Digestive System Diseases. [PDF]

open access: yesInt J Mol Sci, 2023
Acrolein, a highly reactive α,β-unsaturated aldehyde, is a compound involved in the pathogenesis of many diseases, including neurodegenerative diseases, cardiovascular and respiratory diseases, diabetes mellitus, and the development of cancers of various
Hikisz P, Jacenik D.
europepmc   +2 more sources

Pathophysiological role of BACH transcription factors in digestive system diseases. [PDF]

open access: yesFront Physiol, 2023
BTB and CNC homologous (BACH) proteins, including BACH1 and BACH2, are transcription factors that are widely expressed in human tissues. BACH proteins form heterodimers with small musculoaponeurotic fibrosarcoma (MAF) proteins to suppress the ...
Song Q, Mao X, Jing M, Fu Y, Yan W.
europepmc   +2 more sources

The pathophyiological role of aminoacyl-tRNA synthetases in digestive system diseases. [PDF]

open access: yesFront Physiol, 2022
Aminoacyl-tRNA synthetases (ARSs) catalyze the ligation of amino acids to their cognate transfer RNAs and are indispensable enzymes for protein biosynthesis in all the cells.
Wusiman W, Zhang Z, Ding Q, Liu M.
europepmc   +2 more sources

Aquaporins: A new target for traditional Chinese medicine in the treatment of digestive system diseases. [PDF]

open access: yesFront Pharmacol, 2022
Aquaporins (AQPs) are a family of transmembrane proteins expressed in various organ systems. Many studies have shown that the abnormal expression of AQPs is associated with gastrointestinal, skin, liver, kidneys, edema, cancer, and other diseases.
Huang Y   +9 more
europepmc   +2 more sources

Pathophysiological Role of Purinergic P2X Receptors in Digestive System Diseases. [PDF]

open access: yesFront Physiol, 2021
P2X receptors (P2XRs) are trimeric, non-selective cation channels activated by extracellular ATP and widely distributed in the digestive system. P2XRs have an important role in the physiological function of the digestive system, such as neurotransmission,
An Q   +11 more
europepmc   +2 more sources

Advancements in NMN biotherapy and research updates in the field of digestive system diseases. [PDF]

open access: yesJ Transl Med
Nicotinamide mononucleotide (NMN), a crucial intermediate in NAD + synthesis, can rapidly transform into NAD + within the body after ingestion. NMN plays a pivotal role in several important biological processes, including energy metabolism, cellular ...
Liao G   +7 more
europepmc   +2 more sources

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