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Novel Molecular Targets in Malignant Diseases of Digestive System [PDF]

Gastroenterology Research and Practice, 2013
Digestive malignancies remain one of the leading causes of cancer-related death worldwide despite the fact that increasing clinical and biological knowledge has emerged. Among all the newly discovered cancer cases, colorectal cancer, stomach cancer, liver cancer, and esophagus cancer rank in the front and the mortality rate for them also tops the list.
Huang, Qin, Jiang, Chunping, Wu, Youmin, Xia, Qiang   +3 more
core   +9 more sources

Conditional Cell Reprogramming in Modeling Digestive System Diseases. [PDF]

Front Cell Dev Biol, 2021
Digestive diseases have become an important source of morbidity and mortality. The considerable financial and health burdens caused by digestive diseases confirm the importance of extensive research to better understand and treat these diseases. The development of reliable preclinical models is essential for understanding the pathogenesis of digestive ...
Zhao R, Li R, An T, Liu X.
europepmc   +6 more sources

Burden of digestive system diseases in China and its provinces during 1990–2019: Results of the 2019 Global Disease Burden Study [PDF]

Chinese Medical Journal
. Background:. Evaluating the impact of digestive system diseases is vital for devising effective prevention strategies. However, comprehensive reports on the burden of digestive system diseases in China are lacking.
Zhiyuan Cheng, Tinglu Wang, Yunfei Jiao, Jinlei Qi, Xun Zhang, Siwei Zhou, Lei Xin, Rong Wan, Maigeng Zhou, Zhaoshen Li, Luowei Wang, Yuanyuan Ji   +11 more
doaj   +2 more sources

Temporal patterns of multiple long-term conditions in individuals with intellectual disability living in Wales: an unsupervised clustering approach to disease trajectories. [PDF]

Front Digit Health
Identifying and understanding the co-occurrence of multiple long-term conditions (MLTC) in individuals with intellectual disabilities (ID) is vital for effective healthcare management. These individuals often face earlier onset and higher prevalence of MLTCs, yet specific co-occurrence patterns remain unexplored.
Kousovista R, Cosma G, Abakasanga E, Akbari A, Zaccardi F, Jun GT, Kiani R, Gangadharan S.   +7 more
europepmc   +2 more sources

Meckel's Diverticulum Perforation by Foreign Body: A Case Report [PDF]

Bulletin of Emergency and Trauma, 2021
Meckel’s diverticulum is the most common gastrointestinal congenital defect, which, although asymptomatic in adults, may present symptoms in obstruction, inflammation, bleeding and foreign body perforation.
José Roberto Alves, Gustavo Busch Justino, Leonardo Busch Justino, Caique Martins Pereira Ternes, João Vítor Ternes Rech, Fabrissio Portelinha Graffunder   +5 more
doaj   +1 more source

Nanodrug delivery materials for digestive system diseases

APL Materials
Digestive system diseases, such as gastritis, gastric ulcers, chronic liver disease, inflammatory bowel disease (IBD), and colorectal cancer, represent a major group of diseases that have high morbidity and death rates worldwide.
Dan Yang, Huanxuan Zeng, Yuan Zhuang, Shicui Jiang, Wenjie Pan   +4 more
doaj   +2 more sources

Expanding the mutational spectrum of ZTTK syndrome: A de novo variant with global developmental delay and malnutrition in a Chinese patient

Molecular Genetics & Genomic Medicine, 2023
Background Zhu‐Tokita‐Takenouchi‐Kim (ZTTK, OMIM 617140) syndrome is a severe multisystem developmental disorder characterized by intellectual disability, developmental delay, cortical malformations, epilepsy, visual problems, musculoskeletal ...
Shuo Tang, Jieyu You, Li Liu, Hongjuan Ouyang, Na Jiang, Jiaqi Duan, Canlin Li, Yanhong Luo, Wenting Zhang, Meizheng Zhan, Chenxi Liu, Gui‐Zhen Lyu, Victor Wei Zhang, Hongmei Zhao   +13 more
doaj   +1 more source

Purification of Porcine Circovirus Type 2 Using an Affinity Chromatography Based on a Neutralizing Monoclonal Antibody against Viral Capsid Protein

Pathogens, 2021
Porcine circovirus type 2 (PCV2) is a DNA virus without an envelope. The viral particle is icosahedral and has a diameter of approximately 17 nm. In order to obtain the purified virus, a broad-spectrum monoclonal antibody 3A5 against PCV2 was coupled to ...
Haiqiao Bian, Chong Yu, Yanwu Wei, Li Feng, Changming Liu, Liping Huang   +5 more
doaj   +1 more source

Recent Trend of Nanotechnology Applications to Improve Bio-accessibility of Lycopene by Nanocarrier: A Review [PDF]

Journal of Food Chemistry and Nanotechnology 8(4): 162-180, 2022, 2023
Lycopene, rich in red, yellow, or orange-colored fruits and vegetables, is the most potent antioxidant among the other carotenoids available in human blood plasma. It is evident that regular lycopene intake can prevent chronic diseases like cardiovascular diseases, type-2 diabetes, hypertension, kidney diseases and cancer.
arxiv   +1 more source

Patient-physician relationships, health self-efficacy, and gynecologic cancer screening among women with Lynch syndrome

Hereditary Cancer in Clinical Practice, 2019
Background Lynch syndrome, a hereditary cancer syndrome, predisposes women to colorectal, endometrial, and ovarian cancer. Current guidelines recommend that women with Lynch syndrome undergo risk-reducing gynecological surgery to reduce their chances of ...
Kaitlin M. McGarragle, Melyssa Aronson, Kara Semotiuk, Spring Holter, Crystal J. Hare, Sarah E. Ferguson, Zane Cohen, Tae L. Hart   +7 more
doaj   +1 more source