Conditional Cell Reprogramming in Modeling Digestive System Diseases [PDF]
Digestive diseases have become an important source of morbidity and mortality. The considerable financial and health burdens caused by digestive diseases confirm the importance of extensive research to better understand and treat these diseases.
Ruihua Zhao+7 more
doaj +7 more sources
Burden of digestive system diseases in China and its provinces during 1990–2019: Results of the 2019 Global Disease Burden Study [PDF]
. Background:. Evaluating the impact of digestive system diseases is vital for devising effective prevention strategies. However, comprehensive reports on the burden of digestive system diseases in China are lacking.
Zhiyuan Cheng+11 more
doaj +3 more sources
Lactobacillus reuteri in digestive system diseases: focus on clinical trials and mechanisms. [PDF]
Objectives Digestive system diseases have evolved into a growing global burden without sufficient therapeutic measures. Lactobacillus reuteri (L.
Peng Y+5 more
europepmc +2 more sources
Applications and Prospects of Artificial Intelligence-Assisted Endoscopic Ultrasound in Digestive System Diseases. [PDF]
Endoscopic ultrasound (EUS) has emerged as a widely utilized tool in the diagnosis of digestive diseases. In recent years, the potential of artificial intelligence (AI) in healthcare has been gradually recognized, and its superiority in the field of EUS ...
Huang J, Fan X, Liu W.
europepmc +2 more sources
Diet as a Source of Acrolein: Molecular Basis of Aldehyde Biological Activity in Diabetes and Digestive System Diseases. [PDF]
Acrolein, a highly reactive α,β-unsaturated aldehyde, is a compound involved in the pathogenesis of many diseases, including neurodegenerative diseases, cardiovascular and respiratory diseases, diabetes mellitus, and the development of cancers of various
Hikisz P, Jacenik D.
europepmc +2 more sources
Pathophysiological role of BACH transcription factors in digestive system diseases. [PDF]
BTB and CNC homologous (BACH) proteins, including BACH1 and BACH2, are transcription factors that are widely expressed in human tissues. BACH proteins form heterodimers with small musculoaponeurotic fibrosarcoma (MAF) proteins to suppress the ...
Song Q, Mao X, Jing M, Fu Y, Yan W.
europepmc +2 more sources
The pathophyiological role of aminoacyl-tRNA synthetases in digestive system diseases. [PDF]
Aminoacyl-tRNA synthetases (ARSs) catalyze the ligation of amino acids to their cognate transfer RNAs and are indispensable enzymes for protein biosynthesis in all the cells.
Wusiman W, Zhang Z, Ding Q, Liu M.
europepmc +2 more sources
Aquaporins: A new target for traditional Chinese medicine in the treatment of digestive system diseases. [PDF]
Aquaporins (AQPs) are a family of transmembrane proteins expressed in various organ systems. Many studies have shown that the abnormal expression of AQPs is associated with gastrointestinal, skin, liver, kidneys, edema, cancer, and other diseases.
Huang Y+9 more
europepmc +2 more sources
Pathophysiological Role of Purinergic P2X Receptors in Digestive System Diseases. [PDF]
P2X receptors (P2XRs) are trimeric, non-selective cation channels activated by extracellular ATP and widely distributed in the digestive system. P2XRs have an important role in the physiological function of the digestive system, such as neurotransmission,
An Q+11 more
europepmc +2 more sources
Advancements in NMN biotherapy and research updates in the field of digestive system diseases. [PDF]
Nicotinamide mononucleotide (NMN), a crucial intermediate in NAD + synthesis, can rapidly transform into NAD + within the body after ingestion. NMN plays a pivotal role in several important biological processes, including energy metabolism, cellular ...
Liao G+7 more
europepmc +2 more sources