Results 131 to 140 of about 1,671,138 (344)

A novel antigenic epitope identified on the accessory protein NS6 of porcine deltacoronavirus

Virus Research
Porcine deltacoronavirus (PDCoV) is a novel enteric coronavirus that can cause vomiting, watery diarrhea in pigs and the death of piglets. The open reading frame (ORF) 5 is one of the accessory genes in PDCoV genome and encodes an accessory protein NS6 ...
Qiuge Liu, Jianxiao Wu, Na Gao, Xiaorong Zhang, Mingze Gao, Xin Zhang, Longjun Guo, Yang Wu, Da Shi, Hongyan Shi, Jianfei Chen, Li Feng   +11 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

アコヤガイ由来抗菌物質の性状に関する研究 [PDF]

, 2017
東京海洋大学博士学位論文 平成28年度(2016) 応用生命科学 課程博士 甲第427号指導教員: 石崎松一郎全文公表年月日: 2018-07 ...
林 海生
core   +1 more source

Verified and potential pathogens of predatory mites (Acari: Phytoseiidae) [PDF]

, 2008
Several species of phytoseiid mites (Acari: Phytoseiidae), including species of the genera Amblyseius, Galendromus, Metaseiulus, Neoseiulus, Phytoseiulus and Typhlodromus, are currently reared for biological control of various crop pests and/or as model ...
A Janssen, A Jeyaprakash, AR Weeks, AR Weeks, AR Weeks, AR Weeks, B Lighthart, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, C Schütte, D Skirvin, D Skirvin, DA Raworth, DC Margolies, DG Boucias, DL Johanowicz, DL Johanowicz, DL Johanowicz, DL Johanowicz, DR Horton, DS Yao, E Zchori-Fein, E Zchori-Fein, EAM Beerling, EAM Beerling, EAM Beerling, ES Arutunyan, G Poinar, G Šut’áková, G Šut’áková, G Šut’áková, G Šut’áková, G Šut’áková, G Šut’áková, GJ Moraes De, H Evans, IP Furtado, JA McMurtry, JAJ Breeuwer, JC Lenteren van, JC Lenteren van, JJ Becnel, LA Corpuz-Raros, LE Olsen, LK Tanigoshi, LK Tanigoshi, LPS Geest van der, M Dicke, M Dicke, M Dicke, M Enigl, M Enigl, M Vrie van de, MA Hoy, ME Courcy Williams De, ME Huigens, MS Hunter, MW Sabelis, MW Sabelis, MY Steiner, MY Steiner, MY Steiner, P Schausberger, PP Sikorowski, R Gols, R Pukall, R Stouthamer, R Stouthamer, R Zemek, RT Hess, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Bjørnson, S Blümel, S Keller, T Maeda, T Maeda, TG Andreadis, TVM Groot, Y Tanada   +89 more
core   +2 more sources

The parasympathetic and sensory innervation of the proximal and distal colon in male mice

Frontiers in Neuroanatomy
IntroductionThe distributions of extrinsic neurons innervating the colon show differences in experimental animals from humans, including the vagal and spinal parasympathetic innervation to the distal colon.
Lixin Wang, Lixin Wang, Yvette Taché, Yvette Taché   +3 more
doaj   +1 more source

Dataset for evaluation of threescoring systems for forecasting the clinical outcomes of patients with upper gastrointestinal bleeding (UGIB) – Ahvaz, Iran

Data in Brief, 2018
Upper gastrointestinal bleeding (UGIB) which occurs proximal to the Treitz ligament is one of the most common cases is emergency medical conditions. The aim of this data article is to evaluation of Rockall and Blatchford scoring systems for predicting ...
Seyed Saeidseyedian, Ali Akbar Shayesteh, Fereshteh Beyranvandi   +2 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Association of mutations in the basal core promoter and pre-core regions of the hepatitis B viral genome and longitudinal changes in HBV level in HBEAG negative individuals: Results from a cohort study in northern Iran [PDF]

, 2015
Background: Although certain HBV mutations are known to affect the expression of Hepatitis e antigen, their association with HBV viral level or clinical outcomes is less clear.
Besharat, S., Freedman, N.D., Katoonizadeh, A., Malekzadeh, R., Mohamadkhani, A., Moradi, A., Poustchi, H., Roshandel, G.   +7 more
core   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source