Results 221 to 230 of about 1,144,886 (364)

Application of network pharmacology in traditional Chinese medicine for the treatment of digestive system diseases. [PDF]

open access: yesFront Pharmacol
Zheng S   +11 more
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

Life Style-Related Diseases of the Digestive System: Endocrine Disruptors Stimulate Lipid Accumulation in Target Cells Related to Metabolic Syndrome

open access: bronze, 2007
Koichiro Wada   +6 more
openalex   +2 more sources

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

open access: yesAdvanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li   +12 more
wiley   +1 more source

Cholelithiasis - current knowledge about one of the most common diseases of the digestive system

open access: diamond, 2023
Gabriela Demidowicz   +9 more
openalex   +2 more sources

Research progress on the roles of dopamine and dopamine receptors in digestive system diseases. [PDF]

open access: yesJ Cell Mol Med
Lu X   +13 more
europepmc   +1 more source

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