Research progress on NUSAP1 and its role in digestive system neoplasms [PDF]
Frontiers in OncologyNucleolar spindle-associated protein 1 (NUSAP1) is a microtubule-binding protein critical in the mitotic cell cycle. Its primary functions encompass maintaining microtubule stability, facilitating spindle assembly, regulating chromosome alignment, and ...
Shangui Fu +3 more
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Solute carrier transporters: potential targets for digestive system neoplasms [PDF]
Cancer Management and Research, 2018 Jing Xie,1,2 Xiao Yan Zhu,1,2 Lu Ming Liu,1,2 Zhi Qiang Meng1,2 1Department of Integrative Oncology, Fudan University Shanghai Cancer Center, 2Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, People’s Republic of
Xie J, Zhu XY, Liu LM, Meng ZQ
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The Applications of Artificial Intelligence in Digestive System Neoplasms: A Review [PDF]
Health Data Science, 2023 Importance: Digestive system neoplasms (DSNs) are the leading cause of cancer-related mortality with a 5-year survival rate of less than 20%. Subjective evaluation of medical images including endoscopic images, whole slide images, computed tomography ...
Shuaitong Zhang +11 more
doaj +4 more sources
Burden of digestive system neoplasms in middle-aged and elderly adults: Temporal trends and geographic disparities (1990-2021). [PDF]
PLoS ONEObjectiveThis study aims to comprehensively analyze the temporal trends and geographic disparities in the burden of seven digestive system neoplasms-esophageal cancer, stomach cancer, colon and rectum cancer, liver cancer, gallbladder and biliary tract ...
Yinying Chai +5 more
doaj +3 more sources
CircRNAs: a new target for the diagnosis and treatment of digestive system neoplasms [PDF]
Cell Death and Disease, 2021 A circRNA is a type of endogenous noncoding RNA that consists of a closed circular RNA molecule formed by reverse splicing; these RNAs are widely distributed in a variety of biological cells. In contrast to linear RNAs, circRNAs have no 5′ cap or 3′ poly(
Jie Li +7 more
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The Role of Intracellular Lipid-Binding Proteins in Digestive System Neoplasms [PDF]
Current OncologyIntracellular lipid-binding proteins (iLBPs) are key mediators of intracellular transport for fatty acids and retinoids, functioning as lipid chaperones.
Christos Kakouratos +3 more
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Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms. [PDF]
Recent Pat Anticancer Drug DiscovDigestive system neoplasms are highly heterogeneous and exhibit complex resistance mechanisms that render anti-programmed cell death protein (PD) therapies poorly effective. The tumor microenvironment (TME) plays a pivotal role in tumor development, apart from supplying energy for tumor proliferation and impeding the body's anti-tumor immune response,
Wu Y +6 more
europepmc +4 more sources
Prognostic Value of NME1 (NM23-H1) in Patients with Digestive System Neoplasms: A Systematic Review and Meta-Analysis. [PDF]
PLoS ONE, 2016 ObjectiveThere is a heated debate on whether the prognostic value of NME1 is favorable or unfavorable. Thus, we carried out a meta-analysis to evaluate the relationship between NME1 expression and the prognosis of patients with digestive system neoplasms.
Wei Han +12 more
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CircRNA-Encoded Peptides or Proteins as New Players in Digestive System Neoplasms [PDF]
Frontiers in Oncology, 2022 Circular RNAs (circRNAs) were considered non-coding RNAs. Nowadays, a large number of studies have found that these RNAs contain open reading frames that can be translated in a cap-independent manner, such as internal ribosome entry site (IRES) and N6 ...
Enqing Meng +3 more
doaj +2 more sources
Systematic Analysis of Molecular Characterization and Clinical Relevance of Liquid–Liquid Phase Separation Regulators in Digestive System Neoplasms [PDF]
Frontiers in Cell and Developmental Biology, 2022 Background: The role of liquid–liquid phase separation (LLPS) in cancer has also attracted more and more attention, which is found to affect transcriptional regulation, maintaining genomic stability and signal transduction, and contribute to the ...
Yaxin Zhang +6 more
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