Results 121 to 130 of about 43,606 (204)

Machine Learning‐Informed Nano Co‐Assembly Inhibits Fibroblast Activation Protein and Improves Drug Delivery in Fibrotic Tissue

Advanced Materials, EarlyView.
We present SP‐13786 (SP), a fibroblast activation protein (FAP) inhibitor, as a universal excipient for co‐assembling stable drug nanoparticles (SCAN). Assembly mechanism deciphered by molecular dynamics and explainable machine learning, SCAN attenuate fibrosis‐induced stromal barriers, enhances lesional drug accumulation, and improves therapeutic ...
Zehua Liu, Qiang Long, Yihao Liu, Xiuqiao Sun, Baoding Zhang, Binxin Liao, Weibin Wu, Wangxi Hai, Pei Zhang, Wenhua Lian, Yuewen Zhu, Zheng Wang, Caisheng Wu, Xianming Deng, Hélder A. Santos, Xiaofeng Ye   +15 more
wiley   +1 more source

Chinese clinical practice guidelines for super minimally invasive surgery of digestive tract tumors. [PDF]

J Transl Int Med
Chen Q, Yuan Y, Li H, Sun Y, Zhu X, Zhai Y, Liu M, Lyu K, Ning B, Shao Q, Xu J, Zhang Z, Li Y, Tian S, Zuo X, Han K, Wang J, Du C, Zhang L, Du J, Liu L, Chen X, Linghu E, Chinese Society of Digestive Endoscopy, SMIS Committee of World Endoscopy Organization.   +24 more
europepmc   +1 more source

Building like a Coral—Parallelized, Multiscale Biofabrication

Advanced Materials, EarlyView.
Corals build stiff, strong, and inherently circular skeletal materials under resource‐ and energy‐limited conditions—offering blueprints for transformative materials. We synthesize the current understanding of coral biomineralization and reframe coral growth as a multiscale, parallelized biofabrication process.
Asma Rehman, Marta Peña Fernández, Kristina K. Beck, Gavin L. Foster, Sebastian J. Hennige, Uwe Wolfram   +5 more
wiley   +1 more source

The development and application of magnetic surgery in clinical treatment. [PDF]

Biomed Eng Online
Liu L, Xu S, Bai S, Xu J, Li Y, Bonavina L, Lee D, Xiang L, Dong D, Dong J, Lyu Y.   +10 more
europepmc   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

Advanced Materials Interfaces, EarlyView.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez, Eaazhisai Kandiah, Sofia Leo, Erwan Dupont, Fabrizio Johnson‐Corrales, Marc‐André Hograindleur, Sarvenaz Keshmiri, Hélène Elleaume, Benoit Busser, Romain Haudecoeur, Véronique Jacob, Anthony Vella, Véronique Josserand, Maxime Henry, Jean‐Luc Coll, Amandine Hurbin, Xavier Le Guével, Mans Broekgaarden   +17 more
wiley   +1 more source

Robot-Assisted Abdominoperineal Resection for Anal Fistula Cancer in a Patient with Situs Inversus Totalis: A Case Report. [PDF]

Surg Case Rep
Kita Y, Mori S, Tsuruta Y, Hirano T, Iio S, Utsunomiya A, Iino S, Maemura K.   +7 more
europepmc   +1 more source

Advanced Mounting Technique for Improved Imaging and Analysis of Embedded Spheroids and Migrating Cells in Light Sheet Fluorescence Microscopy

Advanced Materials Technologies, EarlyView.
A novel sample holder compatible with the Zeiss Lightsheet 7 microscope improves imaging of spheroids embedded in collagen matrices. By enabling dual‐sided illumination, it enhances image quality and quantitative analysis of migrating cells. This method advances 3D light sheet microscopy for studying tumor invasion and therapeutic responses.
Masoumeh Mohamadian Namaqi, Franziska Moll, Robert Römer, Andreas Grodrian, Doris Heinrich, Karen Lemke   +5 more
wiley   +1 more source

Perioperative multidisciplinary nursing model for endoscopic gastric submucosal dissection development and effect evaluation. [PDF]

World J Gastrointest Surg
Qian YP, Cai H, Tang SY, Zhou HP, Han Q, Tu HM.   +5 more
europepmc   +1 more source

Food‐Based Edible Wireless Sensing Device with Isotropic Electromagnetic Response for Gastrointestinal Monitoring

Advanced Materials Technologies, EarlyView.
A sensor is fabricated that reflects electromagnetic waves wirelessly using only edible materials. The substrate is made of edible materials such as sugar and starch, and the electrodes are made of gold. This sensor has isotropic electromagnetic wave characteristics in response to rotation.
Ryosuke Matsuda, Kentaro Tomita, Shion Miura, Michiyuki Satoh, Tetsuo Kan, Hiroaki Onoe   +5 more
wiley   +1 more source