Results 191 to 200 of about 45,629 (269)

Optimal endoscopic drainage strategy for concomitant biliary and gastric outlet obstruction: a multicenter retrospective study (ENDO-GOBO). [PDF]

Ther Adv Gastroenterol
Beuchard T, Ratone JP, Schaefer M, Barthet M, Guilmoteau T, Wallenhorst T, Yassin S, Fayyaz F, Perez-Cuadrado-Robles E, Debourdeau A, Leblanc S, Legros R, Lepetit H, Dahan M, Caillol F, Giovannini M, Chevaux JB, Bouteiller I, Gasmi M, Lorenzo D, Poincloux L, Grainville T, Chen YI, Khashab M, Lepilliez V, Napoleon B, Spadaccini M, Dahel Y, Gonzalez JM, Jacques J, Albouys J.   +30 more
europepmc   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Safety and effectiveness of the Colovac anastomosis protection device compared with diverting ileostomy after low anterior resection: protocol for an international, multicentre, prospective, non-randomised comparative study (SAFE-3). [PDF]

BMJ Open Gastroenterol
Pastier C, Sylla P, Lee SW, Spinelli A, Komen N, Marks J, Martz J, Rhee R, Maykel J, Marcet J, Denost Q, Zaghiyan K, Davids JS, Paluvoi N, Hiller D, McLemore EC, Maggiori L, D'hoore A, Jafari MD, Poylin V, Buzas CJ, Tuech JJ, Lefèvre JH.   +22 more
europepmc   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Protocol for heterotopic mouse intestinal transplantation to study transplant immunology. [PDF]

STAR Protoc
Matsushima H, Soyama A, Hashimoto K, Morita-Nakagawa M, Datta S, Fujiki M, Abu-Elmagd K, Fujita T, Askeyev B, Miyamoto D, Hamada T, Adachi T, Eguchi S.   +12 more
europepmc   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Flexible steerable intraluminal robots during complex procedures : assistance through high-level control

Flexible steerable intraluminal robots have been developed to navigate, inspect and perform complex surgical procedures inside the patient's digestive system, reducing the high incidence and mortality rate of colorectal cancer.
Gonzalez-Herrera, Fernando
core  

Development of a Robotic Training Curriculum for Visceral and Gastrointestinal Surgical Trainees: An International Delphi Study. [PDF]

United European Gastroenterol J
Fadel MG, Walshaw J, Yiasemidou M, Boal M, Pecchini F, Elhadi M, Massey LH, Carrano FM, Fehervari M, Walsh CM, Boshier PR, Eckhoff J, Buckle P, ERSC Study Group, Gisbertz SS, Bouvy N, Arezzo A, Perretta S, Nickel F, Khan J, Hanna GB, Seeliger B, Antoniou SA, Fuchs HF, Francis NK, Kontovounisios C.   +25 more
europepmc   +2 more sources

Prospects for fistula technologies in the study of digestion and metabolism in birds. [PDF]

Front Physiol
Vertiprakhov VG, Zaitsev SY.
europepmc   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source