Results 231 to 240 of about 45,629 (269)

The Impact of Malnutrition Risk and Perioperative Complications in Gastrointestinal Cancer Patients Undergoing Elective Major Surgery: A Prospective Observational Multicenter Study. [PDF]

Nutrients
Durán-Poveda M, Rodríguez Caravaca G, Suárez-de-la-Rica A, Rodríguez Villar D, Pernaute AS, Cancer Minchot E, Bretón JO, Díaz-Vico T, Martínez-Amores B, PREMAS Study Group.   +9 more
europepmc   +1 more source

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Successful Closure of Multiple Post-bariatric Surgery Fistulas Using Modified Internal and External Endoscopic Vacuum Therapy: A Case Report. [PDF]

Cureus
Lata Guacho JA, Simas de Lima M, Sánchez León JA, Ruiz Sosa CA, Valdivieso Maggi JA, Suárez Caicedo MN.   +5 more
europepmc   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Conversion of endoscopic nasobiliary drainage into internal drainage versus endoscopic biliary stenting for benign biliary obstruction: a retrospective propensity score-matched comparative study. [PDF]

Ther Adv Gastroenterol
Zhao Y, Wei Y, Wang J, Sun C, Li W, Wang Y, Li P, Wang W.   +7 more
europepmc   +1 more source

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Identification and prediction of patients eligible for augmented rehabilitation in emergency gastrointestinal surgery (RAUCisable): A protocol for a single-centre, retrospective, observational study. [PDF]

PLoS One
Arnaud É, Dequen G, Chivé É, Lignier D, Gacquer W, Diouf M, Balcaen T, Ghazali DA, Regimbeau JM.   +8 more
europepmc   +1 more source

Endoscopic management of duodenal perforations during endoscopic ultrasound: a case series. [PDF]

Front Med (Lausanne)
Zhang C, Zhang S.
europepmc   +1 more source