Results 71 to 80 of about 45,629 (269)

Surgical outcome of a double versus a single pancreatoduodenectomy per operating day

open access: yes, 2023
Background: For logistical reasons, some high-volume centers have developed surgical programs wherein 1 surgical team performs 2 pancreatoduodenectomies on a single day.
Zonderhuis, Babs M.   +9 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

What is the suggested time interval to change surgical gloves? An integrative review

open access: yes, 2016
To change gloves during a procedure constitutes an important measure to maintain its integrity and to prevent infection in the surgical site, however, there is little consensus regarding the time for these changes.
Camila Sarmento Gama   +2 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Short-term outcomes in minimally invasive versus open gastrectomy: the differences between East and West. A systematic review of the literature

open access: yes, 2018
Objective: Minimally invasive surgical techniques for gastric cancer are gaining more interest worldwide. Several Asian studies have proven the benefits of minimally invasive techniques over the open techniques.
Straatman, Jennifer   +4 more
core   +1 more source

Gangrene of the right colon after blast injury caused by abdominal gunshot wounds [PDF]

open access: yesVojnosanitetski Pregled, 2005
Aim. To present a patient with an indirect secondary nonperforating blast injury of the right colon following abdominal gunshot injury, which led to necrosis and the right colon gangrene, and was surgically managed. Case report.
Ignjatović Dragan   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Anorectal Malformations

open access: yes, 2016
Anorectal malformations (ARMs) are rare birth defects of the digestive system affecting 2–6 per 10.000 births worldwide. These anomalies are the result of an abnormal development of the distal end of the digestive tract interesting the anus and/or rectum
Tommaso Gargano   +3 more
core   +1 more source

Meshless treatment of open inguinal hernia repair: a prospective study

open access: yesEinstein (São Paulo)
OBJECTIVE: To evaluate two types of meshless open inguinal repair and to evaluate the recurrence rate. METHODS: We operated on sequentially 98 men and 15 women with 144 unilateral or bilateral inguinal hernias between December 1988 and April 2007.
Paulo Kassab   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy