Results 51 to 60 of about 1,384,232 (249)

Uncut Esophagojejunostomy with Double Jejunal Pouch: An Alternative Reconstruction Method that Improves the Quality of Life of Patients after Total Gastrectomy

Journal of Investigative Surgery, 2017
Background: Currently, there is no optimal digestive tract reconstruction technique well recognized by scholars after total gastrectomy. In this study, a new reconstruction method, which is modified from the classic Roux-en-Y procedure, an uncut jejunal ...
Jia Qing Gong, Yong Kuan Cao, Guo Hu Zhang, Pei Hong Wang, Guo De Luo   +4 more
doaj   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source

Multiscale Coupling From Mastication to Retronasal Aroma Perception: The PG‐DTCFN Model and Multiphysics Simulation

Advanced Science, EarlyView.
Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen, Xiongfeng He, Zihao Li, Zidong Chen, Jiajin Sun, Xinyu Jiang, Yunhui Zhang, Lizhang Wu, Ran Wang, Jingnan Lu, Bo Wang, Kezhou Cai, Baocai Xu   +12 more
wiley   +1 more source

Biofabrication and biomaterials for urinary tract reconstruction [PDF]

, 2017
Moustafa M Elsawy,1–3 Achala de Mel1 1Division of Surgery and Interventional Science, Royal Free Hospital, NHS Trust, University College London (UCL), 2Division of Reconstructive Urology, University College London Hospitals (uclh), London, UK ...
de Mel A, Achala de Mel, Elsawy MM, Moustafa Elsawy   +3 more
core   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

Reconstruction of Phonated Speech from Whispers Using Formant-Derived Plausible Pitch Modulation [PDF]

, 2015
Whispering is a natural, unphonated, secondary aspect of speech communications for most people. However, it is the primary mechanism of communications for some speakers who have impaired voice production mechanisms, such as partial laryngectomees, as ...
Sharifzadeh, Hamid Reza, McLoughlin, Ian V., Song, Yan, Tan, Su Lim, Li, Jingjie   +4 more
core   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

Application of λ esophagojejunostomy in total gastrectomy under laparoscopy: a modified technique for post-gastrectomy reconstruction

Frontiers in Oncology
ObjectiveCommon gastrectomy methods can significantly affect patients’ postoperative quality of life. This study investigated the safety, feasibility, and short-term efficacy of λ-type esophagojejunostomy in total gastrectomy under total laparoscopy ...
Lang-Biao Liu, Lang-Biao Liu, Guo-Tian Ruan, Guo-Tian Ruan, Ya-Dong Wu, Ya-Dong Wu, Lei Niu, Lei Niu, Jun Cai, Jun Cai   +9 more
doaj   +1 more source

Minimally invasive techniques and indocyanine angiography in anterior abdominal wall reconstruction after multiple laparotomies

Videosurgery and Other Miniinvasive Techniques, 2018
Anterior abdominal wall reconstruction surgery in patients who have undergone multiple laparotomies is associated with a high risk of complications. For this reason, minimally invasive surgery techniques are used to avoid abdominal compartment syndrome ...
Tomasz Buczek, Wiesław Tarnowski, Marcin Kuriata, Maciej Śmietański   +3 more
doaj   +1 more source

A study of the perceived risks, benefits and barriers to the use of SDD in adult critical care units (the SuDDICU study) [PDF]

, 2010
Peer ...
Campbell, MK, L MacIntyre, Seppelt I, Cuthbertson BH, J Francis, Grimshaw, J. M., MacIntyre L, BH Cuthbertson, Macintyre, L., Grimshaw, J, Seppelt, I., I Seppelt, Cuthbertson, B H, Francis, J., MacIntyre, L, Francis J, Campbell, M K, Cuthbertson, B. H., Campbell MK, Campbell, M. K., null null, Cuthbertson, BH, J Grimshaw, Seppelt, I, Francis, J, MK Campbell, Grimshaw J, SuDDICU study groups   +27 more
core   +2 more sources