Results 111 to 120 of about 614,548 (300)

A preclinical mouse model mimicking the ovarian cancer‐induced estrogen deficiency‐depression axis

Animal Models and Experimental Medicine, EarlyView.
A preclinical mouse model of ovarian cancer–related depression was developed by combining intraperitoneal tumor cell injection, ovariectomy, and chronic restraint stress. The model replicates key clinical features including estrogen deficiency, depressive‐like behaviors, and tumor progression, and provides a reliable tool for studying the endocrine ...
Jiamin Liu, Yafei Yang, Chunxi Liu, Danting Wen, Tingyu Zhao, Ping Xie, Jing Xiao   +6 more
wiley   +1 more source

Digital transformation and EFL anxiety: A mixed-methods study on the impact of online learning on the language acquisition psychology of Saudi Arabian students

Social Sciences and Humanities Open
This study fills a crucial knowledge gap regarding the psychological effects of online language learning in Arab educational contexts by examining how digital transformation influences EFL anxiety among Saudi university students in this institutional ...
Mohammed S. Alharbi
doaj   +1 more source

Sleep-Wake Disorders and a Look at Insomnia through Biological and Behavioral Perspectives [PDF]

, 2017
Insomnia is defined by difficulties in falling asleep, maintaining sleep, and problems with early morning awakenings. Unfortunately, due to these symptoms daytime fatigue often follows.
Fontanarosa, Mia
core   +1 more source

Metformin enhances external urethral sphincter integrity and restores continence via AMPK activation in a rat model of stress urinary incontinence

Animal Models and Experimental Medicine, EarlyView.
The pathogenesis of stress urinary incontinence (SUI) is intimately associated with injury to the external urethral sphincter (EUS). In this study, we established an SUI model induced by double vaginal distension and demonstrated that metformin treatment activated the AMPK signaling in the EUS tissue.
Yuting Xu, Xuhong Li, Alvaro Munoz, Li Jiang, Lihua Huang, Yanhua Zhou, Liping Zhu, Youbo Yang   +7 more
wiley   +1 more source

Digital Financial Literacy and Anxiety About Life After 65: Evidence from a Large-Scale Survey Analysis of Japanese Investors

Risks
In the context of Japan’s rapidly aging population, people’s anxiety about life after 65, especially regarding financial sustainability, has become a growing concern. This study examines old age anxiety through the lens of digital financial literacy (DFL)
Jargalmaa Amarsanaa, Trinh Xuan Thi Nguyen, Yu Kuramoto, Mostafa Saidur Rahim Khan, Yoshihiko Kadoya   +4 more
doaj   +1 more source

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

Animal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu, Jiaqi Chen, Zhonghui Li, Jiamin Zhou, Hui Zhang, Yujia Yu, Feng Cheng, Jie Bao, Chunhan Feng, Xiangqu Yu, Zhao Xia, Rao Ding, Xiang Li   +12 more
wiley   +1 more source

How does digital learning resource accessibility affects math learning anxiety in high school—an empirical analysis based on PISA 2022

Frontiers in Psychology
IntroductionAs math learning anxiety remains a persistent barrier to student achievement and well-being, it is crucial to understand how digital learning environments can alleviate or intensify this issue.MethodsDrawing on large-scale PISA 2022 survey ...
Cunkuan Wang, Guizhen Yang, Haoran Cui, Yuelong Ming, Zhendong Sun   +4 more
doaj   +1 more source

What Twitter Profile and Posted Images Reveal About Depression and Anxiety

, 2019
Previous work has found strong links between the choice of social media images and users' emotions, demographics and personality traits. In this study, we examine which attributes of profile and posted images are associated with depression and anxiety of
Eichstaedt, Johannes C., Guntuku, Sharath Chandra, Preotiuc-Pietro, Daniel, Ungar, Lyle H.   +3 more
core   +1 more source

Multimorbidity and Associations with Cognition and Alzheimer's Disease Biomarkers

Annals of Neurology, EarlyView.
Objective Multimorbidity, the coexistence of 2 or more chronic conditions, has been linked to cognitive aging and Alzheimer's disease (AD) and AD‐related dementias, yet the mechanisms remain unclear. We aimed to examine the associations of multimorbidity with cognition and biomarkers across multiple mechanistic pathways.
Xiaqing Jiang, Sid E. O'Bryant, Robert A. Rissman, Leigh A. Johnson, Meredith N. Braskie, Kristine Yaffe, the HABS‐HD Study Team, Sid E. O'Bryant, Kristine Yaffe, Arthur Toga, Robert Rissman, Leigh Johnson, Meredith Braskie, Kevin King, James R. Hall, Melissa Petersen, Raymond Palmer, Robert Barber, Yonggang Shi, Fan Zhang, Rajesh Nandy, Roderick McColl, David Mason, Bradley Christian, Nicole Phillips, Stephanie Large, Joe Lee, Badri Vardarajan, Monica Rivera Mindt, Amrita Cheema, Lisa Barnes, Mark Mapstone, Annie Cohen, Amy Kind, Ozioma Okonkwo, Raul Vintimilla, Zhengyang Zhou, Michael Donohue, Rema Raman, Matthew Borzage, Michelle Mielke, Beau Ances, Ganesh Babulal, Jorge Llibre‐Guerra, Carl Hill, Rocky Vig   +45 more
wiley   +1 more source

Relationship between digital health literacy, distrust in the health system and health anxiety in health sciences students

BMC Medical Education
Health anxiety is frequently observed in university students in all segments of society. Health anxiety is also frequently encountered in health sciences students, who will play the most effective role in developing and protecting public health in the ...
Erhan Dağ, Yaşar Demir, Zuhal Kayar, Mustafa Nal   +3 more
doaj   +1 more source