Results 71 to 80 of about 614,548 (300)

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

Procrastination and online social anxiety: the mediating role of cognitive overload and the moderating influence of mindfulness

Frontiers in Public Health
In an era of ubiquitous digital communication, online social anxiety has become an increasingly salient issue in the context of digital wellbeing. While procrastination is a known risk factor for psychological distress, the cognitive pathways linking it ...
Shaolei Chen, Zhuoling Xie, Hongjing Wu, Zichuan Song   +3 more
doaj   +1 more source

Cognitive-Behavioral Therapy [PDF]

, 2015
Cognitive-behavioral therapy (CBT) is the merging of behavioral and cognitive therapies that mostly focuses on working with the client in the present. Although there are many approaches to CBT, there tend to be some common features.
Rice, Robert H.
core   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

The Journal of the Center for Interdisciplinary Teaching and Learning [PDF]

, 2018
IMPACT: The Journal of the Center for Interdisciplinary Teaching & Learning is a peer-reviewed, biannual online journal that publishes scholarly and creative non-fiction essays about the theory, practice and assessment of interdisciplinary education ...
Boger, Kathryn D., Bozzone, Donna, Cook, Susan E., Donohue, Micah, Doyle, Mary Beth, Henley, Liz, Meljac, Eric, Powell, Beth, Sharicz, Carol Ann   +8 more
core  

Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons [PDF]

, 2006
Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process.
Ambrose-Lanci, L. M., Gallagher, S. M., Unterwald, E. M., Van Bockstaele, E. J.   +3 more
core   +2 more sources

Temporal Interference Stimulation Enhances Neural Regeneration

Advanced Science, EarlyView.
Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressott, Maria Garcia Garrido, Patrycja Dzialecka, Rachel Man Hoi Law, Roberto Portillo‐Lara, Bethany Geary, Elena Faillace, Shirine Merlo‐Nikpay Aslie, Marcelina Wojewska, Maria Otero‐Jimenez, Martina Genta, Luqiao Tan, Karen Duff, Javier Alegre‐Abarrategui, Rylie Green, Nir Grossmann   +15 more
wiley   +1 more source

Influence of information anxiety on core competency of registered nurses: mediating effect of digital health literacy

BMC Nursing
Background In the information age of health care, nurses often face information overload, leading to negative emotions, e.g., anxiety that may impede the adoption of evidence-based practice and clinical decision-making process. Nurses with higher digital
Bing-Yue Zhao, Mei-Rong Chen, Rong Lin, Yuan-jiao Yan, Hong Li   +4 more
doaj   +1 more source

Digital mindfulness, trait anxiety, and psychological wellbeing: the chain mediating roles of emotion regulation and self-compassion

Frontiers in Education
The increasing prevalence of anxiety among university students highlights the importance of understanding psychological resources associated with wellbeing in digitally mediated contexts.
Abdulnaser Algaralleh, Ahmed Jibreel Matarneh, Salwa Al Majali, Marwan Ibrahim Abdel-Fattah Salameh, Mamdouh Baniah Lafee Al Zaben, Heba Fathy Farag Selim   +5 more
doaj   +1 more source

Using technology to deliver cancer follow-up : a systematic review [PDF]

, 2014
Peer reviewedPublisher ...
A Allen, A Palkhivala, A Sikorskii, A Sikorskii, AC Marcus, AG Ekeland, AG Matthew, AK Sandgren, BJ Davison, Christine Bond, DA Bennett, J Green, J Maddams, J Ricke, JD Harrison, Jenny E Sinclair, JJ Coelho, JL Van den Brink, K Beaver, K Beaver, K Cox, K Hede, K Kroenke, M Okera, ME Brennan, ML Kimman, ML Kimman, ML Kimman, MT Hegel, N Kearney, P Murchie, Peter Murchie, R Hazin, R Lewis, Rebekah Dickinson, RS Weinstein, S Downs, S Hall, S McLean, S Prior, S Sood, S Sudhamony, SK Macbride, Susan Hall, VL1 Franklin, YH Yun   +45 more
core   +2 more sources