Hepatocyte Growth Factor and Digital Clubbing.
The cause of digital clubbing is unknown. Hepatocyte growth factor (HGF) is a pleotrophic factor which has various biological effects. We measured serum HGF in 12 patients with digital clubbing; the underlying diseases of these patients were: lung cancer, 2; cystic fibrosis, 2; idiopathic pulmonary fibrosis, 3; lung cancer with idiopathic pulmonary ...
Toru Ezaki+9 more
semanticscholar +6 more sources
An enlargement of the tips of the fingers or toes and a change in the angle where the nails emerge. It occurs when the amount of soft tissue beneath the nail beds increases.
J. Rutherford
openalex +2 more sources
Progressive furrowing of skin with digital clubbing [PDF]
Answers on p 546. A 27 year old man presented with gradual coarsening of his facial features noticed for the past two years. It was associated with marked oiliness of the facial skin and excessive sweating from the palms and soles. He had also noticed gradual painless swelling of the tips of his fingers and toes since puberty, which had assumed …
Arun C Inamadar+5 more
+8 more sources
Touraine-Solente-Gole syndrome: pathogenic variant in SLCO2A1 presented with polyarthralgia and digital clubbing [PDF]
Background Primary Hypertrophic Osteoarthropathy (PHO), also known as Touraine-Solente-Gole Syndrome, is a rare, multisystemic autosomal recessive disorder caused by pathogenic variants in the 15-hydroxyprostaglandin dehydrogenase (HPGD) or Solute ...
Rafaela Nicolau+7 more
doaj +2 more sources
An Automated Clubbed Fingers Detection System Based on YOLOv8 and U-Net: A Tool for Early Prediction of Lung and Cardiovascular Diseases [PDF]
Background/Objectives: Lung and cardiovascular diseases are leading causes of mortality worldwide, yet early detection remains challenging due to the subtle symptoms. Digital clubbing, characterized by the bulbous enlargement of the fingertips, serves as
Wen-Shin Hsu+4 more
doaj +2 more sources
Clinicopathologic Conference: A Four-Year-Old Child With Digital Clubbing. [PDF]
Schultz K+6 more
europepmc +3 more sources
Digital clubbing: the bad omen that endures
Digital clubbing is an important clinical sign that is usually associated with serious condition. Most of the diseases causing clubbing are thoracic, but it is sometimes seen in gastrointestinal or endocrinal disorders. In heavy smokers, thoracic malignancy is the most important entity that needs to be ruled out in patients who exhibit clubbing.
Maged Hassan, Mahmoud Reda, Rana Rizk
openaire +4 more sources
Quantitation of digital clubbing by shadowgram technique. [PDF]
Finger clubbing was quantified from the magnified silhouette of the right index finger in controls and patients with clubbing, using a simple shadowgram technique. There was good correlation between clinical assessment and measurement of both the profile angle and the hyponychial angle.
A. Omar, D. Sinniah
openaire +4 more sources
A novel mutation in the HPGD gene results in the unusual phenotype of palmoplantar keratoderma with digital clubbing and hyperhidrosis. [PDF]
Stephan C+4 more
europepmc +2 more sources
Palmoplantar keratoderma and digital clubbing in 2 sisters with hypertrophic osteoarthropathy [PDF]
Daniel Eriksson, MD, PhD+5 more
doaj +2 more sources