Results 91 to 100 of about 5,379,261 (318)

Primary School Teacher Educators’ Digital Competence: Perceived Confidence and Continuing Needs for 21st-Century Teaching

open access: yesEducational Process: International Journal
Background/purpose. As digital technologies transform education, primary school teacher educators (PSTEs) play a proactive role in preparing pre-service teachers.
Trinh Thi Huong   +3 more
doaj   +1 more source

Les nouvelles monnaies numériques : au-delà de la dématérialisation de la monnaie et de la contestation des banques

open access: yesRevue de la Régulation, 2015
New digital moneys are spreading. Mobil moneys and other cyber moneys merge everywhere in the world and arouse an unexperienced interest. In the early 2000s, there were no more academic controversies, but with new monetary instruments new questions and ...
Alain Laurent, Virginie Monvoisin
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

‘Our Care through Our Eyes’. Impact of a co-produced digital educational programme on nurses’ knowledge, confidence and attitudes in providing care for children and young people who have self-harmed: a mixed-methods study in the UK

open access: yesBMJ Open, 2017
Objectives (1) To determine the impact of a digital educational intervention on the knowledge, attitudes, confidence and behavioural intention of registered children’s nurses working with children and young people (CYP) admitted with self-harm.
J. Manning   +9 more
semanticscholar   +1 more source

Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective A 2‐min digital clock‐drawing test (DCTclock) captures more granular features of the clock‐drawing process than the pencil‐and‐paper clock‐drawing test, revealing more subtle deficits at the preclinical stage of Alzheimer's disease (AD). A previous cross‐sectional study demonstrated that worse DCTclock performance was associated with
Jessie Fanglu Fu   +16 more
wiley   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

Confident, capable and world changing: teenagers and digital citizenship

open access: yesCommunication Research and Practice, 2020
Around the world policymakers are exploring the kinds of skills and competencies that teenagers need to have to contribute to society as digital citizens.
openaire   +3 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

CEO discretion and enterprise digital transformation

open access: yesHeliyon
Digital transformation is a new development opportunity available to enterprises in the digital economy and represents a comprehensive application of digital technology in production, operation, and management.
Yueyun Wang, Zhenhua He
doaj   +1 more source

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