Results 121 to 130 of about 3,055,735 (327)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Digital ruble in the system of digital currencies: opportunities and development prospects

open access: yesВестник университета
Amid deglobalisation, Russia affirms resilience and currency sovereignty. Geopolitical shifts and changing economic situation intensify the need for rapid de-globalisation.
V. A. Logvinov, S. L. Sumbatyan
doaj   +1 more source

Will Digital Currencies Replace Cash?: Digital, Currency, Privacy and Surveillance

open access: yes, 2020
In some nations, including Sweden and South Korea, cash payments are becoming increasingly uncommon. Other nations, such as Germany, continue to predominantly prefer cash. At the same time, digital currency is on the rise, and the announced launch of Facebook’s stablecoin Libra, in particular, has caused a debate around digital money.
Teichmann, Fabian   +1 more
openaire   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

The consequences of digital revolution in monetary realm [PDF]

open access: yesAnali Ekonomskog fakulteta u Subotici, 2018
The digital revolution touches upon every aspect of our life, and accordingly has not circumvented the monetary realm. Three attributes of modern money are still tied to the power of state.
Lukić Velimir, Živković Aleksandar
doaj  

Accounting for Digital Currencies

open access: yesResearch In International Business and Finance, 2023
Miss Noora Alsalmi, S. Ullah, M. Rafique
semanticscholar   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

Blockchain: A Graph Primer

open access: yes, 2017
Bitcoin and its underlying technology Blockchain have become popular in recent years. Designed to facilitate a secure distributed platform without central authorities, Blockchain is heralded as a paradigm that will be as powerful as Big Data, Cloud ...
Akcora, Cuneyt Gurcan   +2 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

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