Results 51 to 60 of about 35,279,699 (295)

The Role of Central Bank Digital Currencies in Financial Inclusion: Asia–Pacific Financial Inclusion Forum 2022

open access: yes, 2023
As digital transformation accelerates globally, new innovative technology solutions to enhance financial inclusion are being developed more rapidly than ever.
Omura, Akihiro   +4 more
core   +1 more source

Exploring the Factors Affecting Countries’ Adoption of Blockchain-Enabled Central Bank Digital Currencies

open access: yesFuture Internet, 2023
Central bank-issued digital currencies have sparked significant interest and are currently the subject of extensive research, owing to their potential for rapid settlement, low fees, accessibility, and automated monetary policies.
Medina Ayta Mohammed   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Digital currencies: Bitcoin [PDF]

open access: yes, 2019
Od leta 2009 in nastanka prve digitalne valute smo dobili še mnoge druge, od katerih jih je veliko propadlo, številne pa so se tudi ohranile. Kljub številčnosti digitalnih valut ostaja bitcoin, ki je prva decentralizirana kriptovaluta, valuta z največjim
Kepnik, Špela
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

A survey of consensus algorithms in public blockchain systems for crypto-currencies

open access: yes, 2021
In recent years, crypto-currencies (a form of decentralised digital currencies) have been quite popular as an alternative form of payments. They are underpinned by a breakthrough technology called Blockchain which extensively use a number of ...
Mohammad Jabed Morshed Chowdhury (9493412)   +2 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Can CBDC Mimic Cash? A Deep Dive into the Digital Euro Case

open access: yes
Central Bank Digital Currencies (CBDCs) are increasingly positioned as digital equivalents to physical cash, yet their ability to replicate the full functionality of cash remains contested.
Patrick Schueffel
core   +1 more source

From Cash to Code: The Transition to Central Bank Digital Currencies in Pakistan [PDF]

open access: yesОблік і фінанси
The introduction of Central Bank Digital Currencies (CBDCs) in Pakistan presents a transformative opportunity to enhance the nation's financial landscape by providing a more efficient, inclusive, and secure medium for financial transactions.
Saeed Ahmed
doaj   +1 more source

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