Results 141 to 150 of about 5,768,137 (296)

New horizons in the role of digital data in the healthcare of older people. [PDF]

open access: yesAge Ageing, 2023
Masoli JAH   +15 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Digital data storage on DNA tape using CRISPR base editors. [PDF]

open access: yesNat Commun, 2023
Sadremomtaz A   +5 more
europepmc   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Applying the digital data and the bioinformatics tools in SARS-CoV-2 research. [PDF]

open access: yesComput Struct Biotechnol J, 2023
Tan M, Xia J, Luo H, Meng G, Zhu Z.
europepmc   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

In-vitro validated methods for encoding digital data in deoxyribonucleic acid (DNA). [PDF]

open access: yesBMC Bioinformatics, 2023
Mortuza GM   +7 more
europepmc   +1 more source

Data reduction complex analog-to-digital data processing requirements for onsite test facilities [PDF]

open access: yes
The analog to digital processing requirements of onsite test facilities are described. The source and medium of all input data to the Data Reduction Complex (DRC) and the destination and medium of all output products of the analog-to-digital processing ...
Debbrecht, J. D.
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

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