Results 61 to 70 of about 5,588,014 (295)

Expressing the tacit knowledge of a digital library system as linked data [PDF]

open access: yes, 2019
Library organizations have enthusiastically undertaken semantic web initiatives and in particular the data publishing as linked data. Nevertheless, different surveys report the experimental nature of initiatives and the consumer difficulty in re-using ...
Di Iorio, A., Schaerf, M.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Co-developing a theory of change for a personalised multimodal cancer prehabilitation programme in South Wales

open access: yesBMC Health Services Research
Background Evidence suggests that prehabilitation interventions, which optimise physical and mental health prior to treatment, can improve outcomes for surgical cancer patients and save costs to the health system through faster recovery and fewer ...
Jack Walklett   +6 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Small and Micro-Water Quality Monitoring Based on the Integration of a Full-Space Real 3D Model and IoT

open access: yesSensors
In order to address the challenges of small and micro-water pollution in parks and the low level of 3D visualization of water quality monitoring systems, this research paper proposes a novel wireless remote water quality monitoring system that combines ...
Yuanrong He   +5 more
doaj   +1 more source

School leadership and educational effectiveness: Lithuanian case in comparative perspective

open access: yesManagement : Journal of Contemporary Management Issues, 2019
This paper examines the links between student learning and school leadership focusing on Lithuania in comparative perspective. Different aspects of school leadership areas are being outlined, but after a more thorough analysis of the educational ...
Rimantas Želvys   +3 more
doaj   +1 more source

The Sloan Digital Sky Survey Quasar Catalog IV. Fifth Data Release [PDF]

open access: yes, 2007
We present the fourth edition of the Sloan Digital Sky Survey (SDSS) Quasar Catalog. The catalog contains 77,429 objects; this is an increase of over 30,000 entries since the previous edition.
Alexander S. Szalay   +45 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Enhancing credit card fraud detection: highly imbalanced data case

open access: yesJournal of Big Data
In the contemporary landscape, fraud is a widespread challenge in today’s financial landscape, requiring innovative methods and technologies to detect and prevent losses from the sophisticated tactics used by fraudsters.
Dalia Breskuvienė, Gintautas Dzemyda
doaj   +1 more source

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