Results 61 to 70 of about 5,768,137 (296)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Device for printing alphanumeric listings and digital data plots [PDF]

open access: yes, 1970
Modified high-speed printer performs x-y plotting of digital data. The device produces a 7-inch square plot with any number of points in less than 25 seconds and has a resolution of 0.2 ...
Oglesbee, J.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Co-developing a theory of change for a personalised multimodal cancer prehabilitation programme in South Wales

open access: yesBMC Health Services Research
Background Evidence suggests that prehabilitation interventions, which optimise physical and mental health prior to treatment, can improve outcomes for surgical cancer patients and save costs to the health system through faster recovery and fewer ...
Jack Walklett   +6 more
doaj   +1 more source

Small and Micro-Water Quality Monitoring Based on the Integration of a Full-Space Real 3D Model and IoT

open access: yesSensors
In order to address the challenges of small and micro-water pollution in parks and the low level of 3D visualization of water quality monitoring systems, this research paper proposes a novel wireless remote water quality monitoring system that combines ...
Yuanrong He   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Digital demodulation with data subcarrier tracking [PDF]

open access: yes, 1970
Digital demodulator is based on early-late bit timing scheme coupled with Costas data tracking loop. System is successful in enhancement of weak signals from space where atmospheric and other interference media cause bit error rate to reach excessive ...
Sanger, D. K.
core   +1 more source

The Sloan Digital Sky Survey Quasar Catalog IV. Fifth Data Release [PDF]

open access: yes, 2007
We present the fourth edition of the Sloan Digital Sky Survey (SDSS) Quasar Catalog. The catalog contains 77,429 objects; this is an increase of over 30,000 entries since the previous edition.
Alexander S. Szalay   +45 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

School leadership and educational effectiveness: Lithuanian case in comparative perspective

open access: yesManagement : Journal of Contemporary Management Issues, 2019
This paper examines the links between student learning and school leadership focusing on Lithuania in comparative perspective. Different aspects of school leadership areas are being outlined, but after a more thorough analysis of the educational ...
Rimantas Želvys   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy