Results 91 to 100 of about 134,422 (303)

Speech Biomarkers From Smartphone Calls Track Progression in REM Sleep Behavior Disorder and Parkinson's Disease

Annals of Neurology, EarlyView.
Objective This 24‐month longitudinal study involving isolated rapid eye movement sleep behavior disorder (iRBD), early‐stage Parkinson's disease (PD), and matched healthy control subjects aimed to assess whether acoustic speech features from real‐world smartphone calls provide passive progressive biomarkers in synucleinopathies.
Michal Šimek, Tereza Tykalová, Michal Novotný, Vojtěch Illner, Tomáš Kouba, Martin Šubert, Pavel Sovka, Jan Švihlík, Evžen Růžička, Karel Šonka, Petr Dušek, Jan Rusz   +11 more
wiley   +1 more source

The applicability of the decisional conflict scale in nursing home placement decision among Chinese family caregivers: A mixed methods approach

, 2017
This study aimed to 1) examine relationships between uncertainty, perceived information, personal values, social support, and filial obligation among Chinese family caregivers faced with nursing home placement of an older adult family member with ...
Chang, Yu-Ping, Schneider, Joanne Kraenzle, Sessanna, Loralee   +2 more
core   +2 more sources

Descriptive, comparative, and functional anatomy of the facial musculature in cattle (Bos taurus)

The Anatomical Record, EarlyView.
Abstract Facial expressions can provide insight into animal emotions and pain, but no standardized system for assessing the entire facial display in cattle (Bos taurus Linnaeus) exists. The Facial Action Coding System (FACS), originally developed for humans, identifies distinct facial movements based on mimetic muscles.
Maja Söderlind, Bridget Cain, Katrina Ask, Jean‐Francois Valarcher, Elin Hernlund, Pia Haubro Andersen, Marie Rhodin   +6 more
wiley   +1 more source

Atypical Visually Guided Precision Grip Control in Middle‐Aged and Older Autistic Adults

Autism Research, EarlyView.
ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle‐aged and older autistic adults or how they relate to demographic factors and autistic traits.
Zheng Wang, Hang Qu, Danielle Christensen, Hanna M. Gemmell, Ellen M. Parks, Kyla E. Wetherington, Ann‐Marie Orlando, Regilda A. Romero, Bikram Karmakar, David E. Vaillancourt   +9 more
wiley   +1 more source

Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy. [PDF]

, 2019
BackgroundProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuronal loss in the extrapyramidal system with pathologic accumulation of tau in neurons and glia.
Dickson, Dennis W, Duara, Ranjan, Graff-Radford, Neil R, Josephs, Keith A, Litvan, Irene, Murray, Melissa E, Sakae, Nobutaka, Uitti, Ryan J, Wszolek, Zbigniew K   +8 more
core   +1 more source

Digital Cognitive Test for Early Detection of Dementia

Dementia poses a significant global health problem, necessitating early detection for effective intervention. A literary review was conducted to examine current mobile-based cognitive tests. The limitations of the reviewed applications varied from accessibility to reliability.
Vasileiou, Olga, Karanikas, Haralampos
openaire   +2 more sources

Aperiodic EEG signatures: unveiling the interplay between APOE ε4 and mild cognitive impairment subtypes

Frontiers in Aging Neuroscience
BackgroundMild cognitive impairment (MCI) is a cognitive decline syndrome in the elderly, often a precursor to dementia. It is a heterogeneous condition that can signal degenerative disorders like Alzheimer’s or non-degenerative conditions such as ...
Joel Eyamu, Joel Eyamu, Boncho Ku, Boncho Ku, Kahye Kim, Kun Ho Lee, Kun Ho Lee, Kun Ho Lee, Jaeuk U. Kim, Jaeuk U. Kim   +9 more
doaj   +1 more source

Transforming Brain Health With Neurotechnology Convergence (Part II): Intelligent Neurointervention Systems for Neurological Disorders

Brain Health, EarlyView.
ABSTRACT Neurological disorders represent a critical domain within global health, necessitating advanced interventions to address complex pathologies such as tumors, functional disorders, and cerebrovascular diseases. Despite the proven benefits of early intervention, current treatment paradigms face significant challenges: (1) limited precision in ...
Qing Ye, Fei Peng, Chao Pan, Ping Zhang, Xuewei Xie, Zixiao Li, Yingxin Tang, Danyang Chen, Yuanwei Li, Jiawen Wu, Zao Han, Qing Dai, Quansheng Gu, Jizong Zhao, Zhouping Tang   +14 more
wiley   +1 more source

Rare manifestation of a c.290 C\u3eT, p.Gly97Glu VCP mutation [PDF]

, 2015
Introduction. The valosin-containing protein (VCP) regulates several distinct cellular processes. Consistent with this, VCP mutations manifest variable clinical phenotypes among and within families and are a diagnostic challenge. Methods.
Chou, Tsui-Fen, Crockett, Cameron D, Gonzalez, Michael A, Grider, Tiffany, Jerath, Nivedita U, Moore, Steven A, Shy, Michael E, Swenson, Andrea, Weihl, Conrad C, Zuchner, Stephan   +9 more
core   +4 more sources

Personalized Multi-Domain Digital Platform for Dementia Prevention

The Personalized Multi-Domain Digital Platform for Dementia Prevention (PM(DP)*2) is a conceptualized evidence-based initiative designed to reduce dementia burden through tailored interventions. By collecting and analyzing multidimensional data on modifiable risk factors, including lifestyle, cardiovascular health, and environmental exposures, the ...
Fereshtehnejad, Seyed-Mohammad, Keshavjee, Karim, Zavar, Abbas   +2 more
openaire   +2 more sources