Results 51 to 60 of about 134,422 (303)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

A Digital Language Coherence Marker for Monitoring Dementia

Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing, 2023
The use of spontaneous language to derive appropriate digital markers has become an emergent, promising and non-intrusive method to diagnose and monitor dementia. Here we propose methods to capture language coherence as a cost-effective, human-interpretable digital marker for monitoring cognitive changes in people with dementia.
Gkoumas, Dimitris, Tsakalidis, Adam, Liakata, Maria   +2 more
openaire   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Beneficial effect of artificial intelligence care call on memory and depression in community dwelling individuals with dementia

Scientific Reports
Traditional dementia-prevention programs have limited accessibility and lack continuous monitoring, making sustained cognitive and emotional support challenging. This study evaluated the effects of artificial intelligence (AI) care calls on the cognitive
Sungwoo Kang, Yunjin Lee, Nayoung Kim, Sang-Houn Ok, Pilsu Kim, Ok-Hyun Park, Da-Mi Kim, Yongwoo Jang, Hee-Jin Kim   +8 more
doaj   +1 more source

Using Digital Media to Improve Dementia Care in India: Protocol for a Randomized Controlled Trial

JMIR Research Protocols, 2022
BackgroundIndia is undergoing a demographic transition characterized by population aging and is witnessing a high dementia rate. Although nearly 7 million people live with dementia in India, dementia awareness is poor, and current
Bianca Brijnath, Upasana Baruah, Josefine Antoniades, Mathew Varghese, Claudia Cooper, Briony Dow, Mike Kent, Santosh Loganathan   +7 more
doaj   +1 more source

Diagnostic accuracy of the Ottawa 3DY and Short Blessed Test to detect cognitive dysfunction in geriatric patients presenting to the emergency department [PDF]

, 2018
ObjectivesCognitive dysfunction (CD) is a common finding in geriatric patients presenting to the emergency department (ED). Our primary objective was to determine the diagnostic accuracy of the Ottawa 3DY (O3DY) and Short Blessed Test (SBT) as screening ...
Barbic, David, Barbic, Skye Pamela, Carpenter, Christopher R, Kemplin, Kate, Kim, Brian, Salehmohamed, Qadeem   +5 more
core   +2 more sources

Ultrasound in Women's Health: Mechanisms, Applications, and Emerging Opportunities

Advanced Materials, EarlyView.
As healthcare moves toward decentralization, ultrasound technologies are evolving from strictly imaging tools in clinical settings into versatile diagnostic and therapeutic platforms, with growing roles addressing women's health needs. This review highlights how ultrasound's underlying physical mechanisms can be harnessed to reduce disparities in women'
Sarah B. Ornellas, Bilal Kizilaslan, Aastha Shah, Jason F. Hou, Yoonsoo Shin, Alejandra Hernandez Moyers, Claudia Lozano, Canan Dagdeviren   +7 more
wiley   +1 more source

Reflections on the Utility of the Retina as a Biomarker for Alzheimer's Disease: A Literature Review. [PDF]

, 2019
As a part of the central nervous system, the retina may reflect both physiologic processes and abnormalities related to diseases of the brain. Indeed, a concerted effort has been put forth to understand how Alzheimer's disease (AD) pathology may manifest
Honma, Patrick, Ngolab, Jennifer, Rissman, Robert A   +2 more
core   +1 more source

Supporting People with Dementia in Digital Social Sharing [PDF]

Proceedings of the 2017 CHI Conference on Human Factors in Computing Systems, 2017
Sharing online is an important way in which people across the lifespan express themselves, maintain relationships, and connect with others. Yet, people with dementia are often not supported in engaging to the full extent of their abilities, particularly in their interaction with online technology.
Amanda Lazar, Caroline Edasis, Anne Marie Piper   +2 more
openaire   +1 more source

Ultra‐Sensitive Nanofiber‐Based Triboelectric Nanogenerator for Energy Harvesting and Self‐Powered Sensing

Advanced Materials, EarlyView.
A multidimensional molecular strategy optimizes the tribonegative layer by electrospinning PVDF‐HFP for dipole alignment and crystallinity, followed by 2D borophene doping to enhance conductivity and charge trapping. Integrated with Nylon‐66 nanofibers, the composite device delivers a record sensitivity of 53.8 ± 1.2 V kPa−1 at 3 Hz, enabling ultra ...
Sajib Roy, Bhaskar Dudem, Md Delowar Hussain, Vlad Stolojan, Seyedeh Sadrieh Emadian, Satheesh Krishnamurthy, Jae Sung Yun, S. Ravi P. Silva   +7 more
wiley   +1 more source