Results 61 to 70 of about 42,554 (282)

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Filament formation associated with spirochetal infection: a comparative approach to Morgellons disease

Clinical, Cosmetic and Investigational Dermatology, 2011
Marianne J Middelveen, Raphael B StrickerInternational Lyme and Associated Diseases Society, Bethesda, MD, USAAbstract: Bovine digital dermatitis is an emerging infectious disease that causes lameness, decreased milk production, and weight loss in ...
Middelveen MJ, Stricker RB
doaj  

Simple and low-cost ways to improve atopic dermatitis treatment outcomes

Лечащий Врач, 2023
Background. According to the Ministry of Health of Russia in the Russian Federation, the prevalence and incidence of atopic dermatitis in the population in 2021 were 390.4 and 155.4 per 100 thousand population, respectively.
T. Yu. Shchegelskaya, O. Ya. Tseytlin, N. B. Migacheva   +2 more
doaj   +1 more source

Topical tacrolimus 0.1% ointment for treatment of cutaneous Crohn's Disease [PDF]

, 2013
Peer reviewedPublisher ...
El-Omar, Emad, Keenan, Ronald A, Ormerod, Anthony D, Rice, Shantini A, Woo, Pick N   +4 more
core   +2 more sources

Quantification of Palmar and Digital Epidermal Thickness and Sweat Duct Density

Clinical Anatomy, EarlyView.
ABSTRACT Palmar digital skin, with its high density of epidermal sweat glands and unique stratum corneum, derives its autonomic innervation from peripheral nerves. Understanding the changes to these structures could serve as objective proxy markers following peripheral nerve injury and interventions to promote regeneration.
Elizabeth Jones, Hanaa N. Mughal, Roxana Moscalu, Malachy Columb, Christopher Duff, Mark Dickinson, Adam J. Reid, Ralph N. A. Murphy   +7 more
wiley   +1 more source

Genome-Wide Association Studies Reveal Susceptibility Loci for Digital Dermatitis in Holstein Cattle

Animals, 2020
Digital dermatitis (DD) causes lameness in dairy cattle. To detect the quantitative trait loci (QTL) associated with DD, genome-wide association studies (GWAS) were performed using high-density single nucleotide polymorphism (SNP) genotypes and binary ...
Ellen Lai, Alexa L. Danner, Thomas R. Famula, Anita M. Oberbauer   +3 more
doaj   +1 more source

Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]

, 2019
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M, Bautista, Diana M, Brem, Rachel B, Brock, Emily C, Deguine, Jacques, Gronert, Karsten, Hill, Rose Z, Kucirek, Natalie, Rifi, Ziad, Schwendinger-Schreck, Jamie, Walsh, Carolyn M, Wei, Jessica   +11 more
core   +1 more source

High‐Frequency Ultrasonographic Characterization of Subcutaneous Glomus Tumors

Journal of Clinical Ultrasound, EarlyView.
Color Doppler image reveals intralesional hypervascularity. ABSTRACT Objective To evaluate the clinical manifestations and ultrasonographic characteristics of glomus tumors under the nails and other subcutaneous soft tissues. Methods A retrospective analysis was performed on 45 patients with pathologically confirmed glomus tumors who underwent ...
Mingyu Bai, Nan Wang, Jie Jiang
wiley   +1 more source

Study on Distribution of Dairy Cattle Hoof Lesions and its Relation to Locomotion Scoring [PDF]

Iranian Journal of Veterinary Surgery, 2007
Objectives- To evaluate the most important bovine digital lesions in Shahrekord area and its correlation with locomotion scoring. Study Design- Cross-Sectional descriptive study. Animals- five hundred and eighteen cows inspected in two seasons.
Ahmad Reza Mohamadnia, Soleiman Kheiri, Hadi Aliabadi, Mojtaba Mohamaddoust, Jamshid Kabiri   +4 more
doaj  

Report from the third international consensus meeting to harmonise core outcome measures for atopic eczema/dermatitis clinical trials (HOME). [PDF]

, 2014
This report provides a summary of the third meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in San Diego, CA, U.S.A., 6-7 April 2013 (HOME III).
Admani, S, Aoki, V, Apfelbacher, C, Ardeleanu, M, Barbarot, S, Berger, T, Bergman, JN, Block, J, Borok, N, Burton, T, Chalmers, JR, Chamlin, SL, Deckert, S, DeKlotz, CC, Dohil, M, Eichenfield, LF, Graff, LB, Hanifin, JM, Hebert, AA, Humphreys, R, Katoh, N, Kisa, RM, Margolis, DJ, Merhand, S, Minnillo, R, Mizutani, H, Nankervis, H, Ohya, Y, Rodgers, P, Schmitt, J, Schram, ME, Simpson, EL, Singh, J, Spuls, P, Stalder, JF, Svensson, A, Takaoka, R, Teper, A, Thomas, KS, Tom, WL, von Kobyletzki, L, Weisshaar, E, Williams, HC, Zelt, S   +43 more
core   +1 more source