Results 71 to 80 of about 35,524,436 (288)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Bridging the Digital Divide

open access: yesDigital Policy Studies
Information and Communication Technology (ICT) is vital for promoting economic participation and growth. However, the prevalence of English as the main language of ICT presents a significant hurdle for many individuals, especially in Africa, hindering ...
Busisiwe Thabisa Sibizo
doaj   +1 more source

Poverty, Literacy, and Social Transformation: An Interdisciplinary Exploration of the Digital Divide

open access: yesJournal of Media Literacy Education, 2018
Harnessing scholarship focused on literacy and poverty, in this article we aim to complicate the common understanding of the digital divide. First, we argue that the dominant literature on the digital divide misses broader connections between ...
Amy J. Bach   +2 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Sociodemographic factors and health digital divide among urban residents: Evidence from a population-based survey in China

open access: yesDigital Health
Background The deep integration of digital technology and healthcare services has propelled the healthcare system into the era of digital health. However, vulnerable populations in the field of information technology, they face challenges in benefiting ...
Yanbin Yang, Chengyu Ma
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Digital Divide Perempuan Indonesia

open access: yesSejarah dan Budaya: Jurnal Sejarah, Budaya, dan Pengajarannya, 2016
Abstrak: Kehadiran teknologi informasi dan komunikasi selama ini telah membawa perubahan bagi masyarakat. Hal itu membawa konsekuensi berupa masalah digital divide bagi negara-negara berkembang seperti Indonesia.
Neni Wahyuningtyas, Khofifatu Rohmah Adi
doaj  

Gender Differences in the Digital Divide, Digital Back-Feeding, and Health-Related Quality of Life Among Rural Older Adults: Cross-Sectional Study

open access: yesJMIR Aging
BackgroundThe digital divide has loomed as a global public issue in recent years. However, evidence is limited regarding whether the digital divide is associated with health-related quality of life (HRQOL) and whether digital back-
Xin Che   +4 more
doaj   +1 more source

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