Results 31 to 40 of about 117,298 (306)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Application of digital elevation model for mapping vegetation tiers
The aim of this paper is to explore possibilities of application of digital elevation model for mapping vegetation tiers (altitudinal vegetation zones).
D. Volařík
doaj +1 more source
Void Filling of Digital Elevation Models With Deep Generative Models [PDF]
5 pages; 4 figures; corrected names in references; clarifications regarding the two generators in the paper; added reference (Borji 2018) on GAN evaluation measures; extended future work discussion; changed (Fig.
Konstantinos Gavriil +2 more
openaire +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
DEVELOPMENT OF A DIGITAL ELEVATION MODEL OF KARA-BOGAZ-GOL BAY
The article presents the results of the efforts to create a digital elevation model of Kara-Bogaz-Gol Bay. The informational background for the digital elevation model was maps of 1:200 000 and 1:100 000 scales. The digital elevation model was created by
Tatiana Vyruchalkina
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Studying relief and landscapes, we often employ digital elevation models. Their applicability is primarily linked to their accuracy. In this paper, we compare the older 100-meter digital elevation model of Slovenia and the more recent 25-meter digital ...
Mauro Hrvatin, Drago Perko
doaj +1 more source
The TanDEM-X Digital Elevation Model and Terrestrial Impact Structures
We utilized the TanDEM-X digital elevation model (DEM) for investigating the complete record of confirmed terrestrial impact structures with respect to its suitability to support geological analysis.
Manfred Gottwald +4 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source

