Results 81 to 90 of about 123,190 (309)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Original LiDAR differential digital elevation model [PDF]

, 2015
Submitted by Kavitha Chandrasekar (kavchand@imail.iu.edu) on 2015-03-10T17:07:44Z No. of bitstreams: 1 Sub_Original_5ft.tif: 2849873792 bytes, checksum: 97fa2aecc8e3f8a2d158ebb480e592d8 (MD5)Made available in DSpace on 2015-03-10T17:07:44Z (GMT). No.
Greenberg, Jonathan A., Rhoads, Bruce L., Berretta, David P., Kumar, Praveen, Garcia, Marcelo H., Holmes, Robert R., Dutta, Debsunder, Goodwell, Allison E., Zhu, Zhenduo, Parker, Gary, Jacobson, Robert B.   +10 more
core  

Sea‐level rise, habitat loss, and potential extirpation of a salt marsh specialist bird in urbanized landscapes

Ecology and Evolution, 2018
Sea‐level rise (SLR) impacts on intertidal habitat depend on coastal topology, accretion, and constraints from surrounding development. Such habitat changes might affect species like Belding's savannah sparrows (Passerculus sandwichensis beldingi; BSSP),
Jordan A. Rosencranz, Karen M. Thorne, Kevin J. Buffington, John Y. Takekawa, Ryan F. Hechinger, Tara E. Stewart, Richard F. Ambrose, Glen M. MacDonald, Mark A. Holmgren, Jeff A. Crooks, Robert T. Patton, Kevin D. Lafferty   +11 more
doaj   +1 more source

Applied spatial analytic tools in orchards with special regard to agro-ecology

International Journal of Horticultural Science, 2011
Our investigation was carried out in several orchards in Hungary. This study reviews applicability of the different spatial analytical techniques in orchard especially models based on surface relief, such as digital elevation model, digital terrain model,
T. Fórián, A. Nagy, J. Tamás, Z. Szabó, M. Soltész, J. Nyéki   +5 more
doaj   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Evaluation of Errors in Digital Terrain Models generated by High Resolution Satellite Images [PDF]

, 2010
Nowadays Digital terrain models play very crucial role in many applications, including engineering to design heavy construction project such as dams, tunnels and highways as well as orthophoto production and modeling and visualization in military ...
Saati, Amirreza
core  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

A Web-based Survey on Digital Elevation Models

Annals of GIS, 2006
Abstract In many earth and environmental science applications, DEMs serve as inputs for detailed spatial analyses, such as the determination of the extent of hydrographic networks, and the classification of terrain for suitability assessments such applications, appreciating the spatial accuracy of the DEM and its variability as a function of location ...
Mandla V. Ravibabu, Kamal Jain
openaire   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source