Results 111 to 120 of about 139,178 (334)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Development of the TanDEM-X Calibration Concept: Analysis of Systematic Errors [PDF]

, 2010
The TanDEM-X mission, result of the partnership between the German Aerospace Center (DLR) and Astrium GmbH, opens a new era in spaceborne radar remote sensing. The first bistatic satellite synthetic aperture radar mission is formed by flying the TanDEM-
Bachmann, Markus, Fiedler, Hauke, Hueso Gonzalez, Jaime, Krieger, Gerhard   +3 more
core   +1 more source

A new 100-m Digital Elevation Model of the Antarctic Peninsula derived from ASTER Global DEM: methods and accuracy assessment

, 2012
. A high resolution surface topography Digital Elevation Model (DEM) is required to underpin studies of the complex glacier system on the Antarctic Peninsula.
A. Cook, T. Murray, A. Luckman, D. Vaughan, N. Barrand   +4 more
semanticscholar   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Digital Elevation Models – From Satellite Images to Free Available DEMs

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Abstract. Digital elevation models are an important component of any Geo-Information System (GIS). This keynote provides an overview of the satellite stereo model orientation and image matching methods currently used to generate Digital Elevation Models (DEMs).
openaire   +3 more sources

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Species-specific forest variable estimation using non-parametric modeling of multi-spectral photogrammetric point cloud data [PDF]

, 2012
The recent development in software for automatic photogrammetric processing of multispectral aerial imagery, and the growing nation-wide availability of Digital Elevation Model (DEM) data, are about to revolutionize data capture for forest management ...
Bohlin, Jonas, Fransson, Johan E.S., Olsson, Håkan, Wallerman, Jörgen   +3 more
core  

Including debris cover effects in a distributed model of glacier ablation [PDF]

, 2012
Distributed glacier melt models generally assume that the glacier surface consists of bare exposed ice and snow. In reality, many glaciers are wholly or partially covered in layers of debris that tend to suppress ablation rates.
Andersen, Anderson, Anderson, Anslow, Arnold, Arnold, B. W. Brock, Bolch, Braithwaite, Brock, Brock, Brock, Dadic, F. Pellicciotti, Foster, Fountain, Hubbard, Intergovernmental Panel on Climate Change, Kellerer-Pirklbauer, Kirkbride, Klok, Kossmann, Lhomme, M. Carenzo, MacDougall, Michlmayr, Mihalcea, Nakawo, Nicholson, Oerlemans, Pellicciotti, Pellicciotti, Pellicciotti, Petersen, Popovnin, Reid, Reijmer, Rye, Scherler, Shea, Shukla, Stokes, Strasser, Swinbank, T. D. Reid, Tenchov, Turnipseed, Zemp, Østrem   +48 more
core   +1 more source

Challenges and Opportunities for UAV-Based Digital Elevation Model Generation for Flood-Risk Management: A Case of Princeville, North Carolina

Italian National Conference on Sensors, 2018
Among the different types of natural disasters, floods are the most devastating, widespread, and frequent. Floods account for approximately 30% of the total loss caused by natural disasters.
L. H. Beni, Jeffery Jones, Gary Thompson, Curt Johnson, A. Gebrehiwot   +4 more
semanticscholar   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source