Results 41 to 50 of about 11,296 (261)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

ASSESSMENT OF REFERENCE HEIGHT MODELS ON QUALITY OF TANDEM-X DEM [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The aim of this study is to investigate the effect of various Global Digital Elevation Models (GDEMs) in producing high-resolution topography model using TanDEM-X (TDX) Coregistered Single Look Slant Range Complex (CoSSC) images.
S. Mirzaee, M. Motagh, H. Arefi
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Flood Inundation Potential Analysis in Denpasar City Using Topographic Wetness Index from Digital Elevation Model

Rekayasa Hijau: Jurnal Teknologi Ramah Lingkungan
ABSTRAK Banjir genangan sering terjadi di wilayah perkotaan, termasuk Kota Denpasar, akibat topografi, karakteristik daerah aliran sungai (DAS), dan perubahan penggunaan lahan. Penelitian ini bertujuan mengidentifikasi potensi genangan banjir menggunakan
Akbar Cahyadhi Pratama Putra, Theresia Puan Bertiana Wardoyo, Ni Putu Nanda Surya Dewi Tilija, Putu Venita Wirastuti, Tantri Utami Widhaningtyas   +4 more
doaj   +1 more source

Vertical accuracy assessment for open-source digital elevation models using GPS control points and watershed basins delineation using GIS

Alexandria Engineering Journal, 2023
Digital elevation models (DEMs) are crucial for numerous assessments of the Earth's surface, so this research aim to evaluate the quality of several open source DEMs like advanced spaceborne thermal emission and reflection radiometer global DEM (ASTER ...
Loutfia Elsonbaty, Hossam El-Din Fawzy, Hossam Mohamed Moghazy, Gehan Rashed, Magda Hamed   +4 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

A comparative analysis of different DEM interpolation methods

Egyptian Journal of Remote Sensing and Space Sciences, 2013
Visualization of geospatial entities generally entails Digital Elevation Models (DEMs) that are interpolated to establish three dimensional co-ordinates for the entire terrain.
P.V. Arun
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A Method for SRTM DEM Elevation Error Correction in Forested Areas Using ICESat-2 Data and Vegetation Classification Data

Remote Sensing, 2022
The past decade has witnessed the rapid development of the SRTM (Shuttle Radar Topography Mission) DEM (digital elevation model) in engineering applications and scientific research.
Yi Li, Haiqiang Fu, Jianjun Zhu, Kefu Wu, Panfeng Yang, Li Wang, Shijuan Gao   +6 more
doaj   +1 more source