Results 31 to 40 of about 60,002 (245)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Method for Measuring the Information Content of Terrain from Digital Elevation Models

Entropy, 2015
As digital terrain models are indispensable for visualizing and modeling geographic processes, terrain information content is useful for terrain generalization and representation.
Lujin Hu, Zongyi He, Jiping Liu, Chunhua Zheng   +3 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Applied spatial analytic tools in orchards with special regard to agro-ecology

International Journal of Horticultural Science, 2011
Our investigation was carried out in several orchards in Hungary. This study reviews applicability of the different spatial analytical techniques in orchard especially models based on surface relief, such as digital elevation model, digital terrain model,
T. Fórián, A. Nagy, J. Tamás, Z. Szabó, M. Soltész, J. Nyéki   +5 more
doaj   +1 more source

Digital Elevation Model Based Hydro‐processing

Geocarto International, 2006
Abstract The article describes a newly implemented routine, called DEM hydro‐processing, which was added to the overall capabilities of the ILWIS-GIS package developed at ITC. A few novel approaches have been incorporated within the package allowing the user to derive a realistic river and basin schematization, e.g.
Maathuis, B.H.P., Wang, Lichun
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Digital elevation models and their use for assessing soil erosion rates on arable lands

Учёные записки Казанского университета: Серия Естественные науки, 2018
The paper presents the results of assessing the accuracy of global digital elevation models (GDEMs), SRTM and ASTER GDEMs, based on a small catchment located on the eastern slope of the Central Russian Upland in the upper reaches of the Veduga River ...
K.A. Maltsev , V.N. Golosov, A.M. Gafurov   +2 more
doaj  

SENSITIVITY ANALYSIS OF UAV-PHOTOGRAMMETRY FOR CREATING DIGITAL ELEVATION MODELS (DEM) [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
This study evaluates the potential that lies in the photogrammetric processing of aerial images captured by unmanned aerial vehicles. UAV-Systems have gained increasing attraction during the last years.
G. Rock, J. B. Ries, T. Udelhoven
doaj   +1 more source

Hydrography‐Driven Coarsening of Grid Digital Elevation Models [PDF]

Water Resources Research, 2018
AbstractA new grid coarsening strategy, denoted as hydrography‐driven coarsening, is developed in the present study. The hydrography‐driven coarsening is designed to retain the essential hydrographic features of valleys and channels observed in high‐resolution digital elevation models: (1) depressions are filled in the considered high‐resolution ...
Moretti G., Orlandini S.
openaire   +5 more sources