Results 71 to 80 of about 61,768 (206)
Efficacy of digital elevation and Nash models in runoff forecast
Digital elevation models (DEMs) are extensively used in hydrological modelling and deriving the geomorphological properties of catchments. Recently, hydrologists have shown interest in researching the effects of DEMs from different sources on simulated ...
Dmitry Kozlov +1 more
doaj +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Quantifying and modeling of stream network using digital elevation models
Quantifying and modeling of stream network using DEMs is the primary objective to understand earth surface processes. In the present study, DEMs of different quality, i.e. resolution, are evaluated for stream network quantification and modeling.
Daisy Paul +2 more
doaj +1 more source
Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones +3 more
wiley +1 more source
ALTIMETRY FITTING METHODS FOR INSAR DIGITAL ELEVATION MODELS
Modelos digitais de elevação (MDE) estão se tornando uma das formas de dados espaciais mais disponíveis e reutilizados nas aplicações de análises geográficas para diversos estudos em ciências da Terra.
Marcos Antônio Timbó Elmiro +2 more
doaj
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji +13 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Digital Elevation Models in Geomorphology
This chapter presents place of geomorphometry in contemporary geomorphology. The focus is on discussing digital elevation models (DEMs) that are the primary data source for the analysis. One has described the genesis and definition, main types, data sources and available free global DEMs.
openaire +5 more sources
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source

