Results 101 to 110 of about 45,677,995 (297)
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Design and development of a user-centred digital library system: some basic guidelines [PDF]
, 2001 Beginning with an introduction and justifications for the need of user-centred digital library development, this paper outlines the architecture, the basic components and functionalities of a Digital Work Environment (DWE) that forms the basis of a user ...
Chowdhury, G., Meyyappan, N., Foo, S.
core +4 more sources
Remote Sensing, 2017 Wetland inundation is crucial to the survival and prosperity of fauna and flora communities in wetland ecosystems. Even small changes in surface inundation may result in a substantial impact on the wetland ecosystem characteristics and function.
Haoming Xia +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source
Digital ecosystems and comparison to existing collaboration environment
, 2006 Digital ecosystems transcend the traditional rigorously defined collaborative environments from centralised, or distributed or hybrid models into an open, flexible, domain cluster, demand-driven interactive environment.
Chang, Elizabeth, West, Martin
core
Ground Rules for Preschooler Exposure to the Digital Environment: A Review of Studies. [PDF]
Psychol Russ, 2023 Nikolaeva EI +3 more
europepmc +1 more source
Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch +9 more
wiley +1 more source
The State of the Kansas Environment, 2010
, 2010 No known reports between 2003 and 2007 2008 onward published biennially The publication of the 2008 Kansas Environment report represents the return to a biennial report for the Division of Environment at the Kansas Department of Health and Environment." -
Kansas. Department of Health and Environment
core +1 more source
Arthritis Care &Research, EarlyView.Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source