Results 51 to 60 of about 45,677,995 (297)

Evaluating the Dominant Controls of Water Erosion in Three Dry Valley Types Using the RUSLE and Geodetector Method

Land, 2021
The dry valley is a unique geographic phenomenon in Southwest China with severe water erosion. However, little is known regarding its dominant controls and the discrepancies between dry valley subtypes, leading to the poor management of water erosion. To
Chao Yang, Jianrong Fan, Jiali Liu, Fubao Xu, Xiyu Zhang   +4 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Identifying high-risk patient clusters for falls using unsupervised machine learning on linked primary and secondary care electronic health record data

Scientific Reports
Falls risk is multifactorial, involving a combination of clinical and sociodemographic factors. Although guidelines acknowledge this complexity, most research has focused on individual risk factors, leaving the combined impact of comorbidities relatively
Rachael Lear, Rachel Tao, Catalina Carenzo, Ekin Yagis, Zhuoyu Li, Maria Tipper, Agnes Motsi, Sharon O’Malley, Yusuf Abdullahi, Ben Glampson, Colin Mitchell, Erik K. Mayer   +11 more
doaj   +1 more source

Pre-Processing Pipeline and Imaging Equipment Impact the Performance of CNN for Breast Cancer Detection in Mammograms: Evidence From CBIS-DDSM and VinDr-Mammo

IEEE Access
Breast cancer is the leading cause of cancer-related death among women worldwide, and its mortality can be significantly reduced through early detection using computer-aided detection (CAD) systems.
Nickerson Ferreira, Andre Peres, Cesar Renno-Costa, Renan C. Moioli   +3 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

OIC-MCE: A Practical Land Cover Mapping Approach for Limited Samples Based on Multiple Classifier Ensemble and Iterative Classification

Remote Sensing, 2020
Land cover samples are usually the foundation for supervised classification. Unfortunately, for land cover mapping in large areas, only limited samples can be used due to the time-consuming and labor-intensive sample collection.
Guangbin Lei, Ainong Li, Jinhu Bian, He Yan, Lulu Zhang, Zhengjian Zhang, Xi Nan   +6 more
doaj   +1 more source

EVALUATION OF ACQUISITION STRATEGIES FOR IMAGE-BASED CONSTRUCTION SITE MONITORING [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016
Construction site monitoring is an essential task for keeping track of the ongoing construction work and providing up-to-date information for a Building Information Model (BIM).
S. Tuttas, S. Tuttas, A. Braun, A. Braun, A. Borrmann, A. Borrmann, U. Stilla, U. Stilla   +7 more
doaj   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Latent Classes of Proximal Traumatic Exposure Among Portuguese Police and Security Professionals: Associations with PTSD Symptoms and Psychological Distress

Psychiatry International
Background: Police and security professionals are routinely exposed to potentially traumatic events as part of occupational duties, placing them at increased risk for post-traumatic stress and broader psychological difficulties.
Hélder António, Sara Albuquerque, Maria Vieira de Castro, Stéphane Bouchard, Pedro Gamito, Ricardo J. Pinto   +5 more
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source