Results 11 to 20 of about 491,937 (246)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Verification of Magnitude and Phase Responses in Fixed-Point Digital Filters
, 2017 In the digital signal processing (DSP) area, one of the most important tasks is digital filter design. Currently, this procedure is performed with the aid of computational tools, which generally assume filter coefficients represented with floating-point ...
Clavier, Laurent +6 more
core +1 more source
Design of frequency invariant beamformer for broadband arrays [PDF]
, 2007 A simple method for the design of a class of arrays with frequency invariant beam patterns is proposed. Starting from the desired frequency invariant beam pattern of an n-D array, the proposed method uses a series of substitutions and an n-D inverse ...
Liu, Wei, Weiss, Stephan
core +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Counting digital filters [PDF]
, 1973 Several embodiments of a counting digital filter of the non-recursive type are disclosed. In each embodiment two registers, at least one of which is a shift register, are included. The shift register received j sub x-bit data input words bit by bit.
Zohar, S.
core +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
A new approach to the realization of low-sensitivity IIR digital filters [PDF]
, 1986 A new implementation of an IIR digital filter transfer function is presented that is structurally passive and, hence, has extremely low pass-band sensitivity. The structure is based on a simple parallel interconnection of two all-pass sections, with each
Mitra, Sanjit K. +2 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
On the eigenfilter design method and its applications: a tutorial [PDF]
, 2003 The eigenfilter method for digital filter design involves the computation of filter coefficients as the eigenvector of an appropriate Hermitian matrix.
Nguyen, Truong Q. +2 more
core
Position estimation delays in signal injection-based sensorless PMSM drives [PDF]
, 2012 The causes of position estimation delays and their effects on the sensorless control of permanent magnet synchronous motor drives are investigated. The position of a permanent magnet synchronous machine is estimated via the injection of high frequency ...
Altomare, A. +3 more
core +1 more source