Results 101 to 110 of about 383,409 (319)

Investors\u27 Asset Allocations versus Life-Cycle Funds

open access: yes, 1999
Life-cycle funds, among the newest asset allocation fund offerings, are managed according to investors\u27 time horizons and risk tolerances. Partly in response to the appearance of these funds, we examined the relationships among the risk in individual ...
Schooley, Diane K., Worden, Debra
core  

2014 Annual Report: A More Giving Australia [PDF]

open access: yes, 2015
Philanthropy Australia defines philanthropy as the planned and structured giving of money, time, information, goods and services, voice and influence to improve the wellbeing of humanity and the community.

core  

Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis

open access: yesAdvanced Science, EarlyView.
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao   +10 more
wiley   +1 more source

Digital Currency in Russia: Legal Foundations and Business Implications

open access: yesЦифровое право
The rapid progress of technology and increasing globalization have led to various outcomes in the financial market. This commentary delves into an effort to incorporate digital financial instruments into Russia’s legal framework, with particular focus on
Yu. V. Brisov, L. A. Abbasova
doaj   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

open access: yesAdvanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng   +9 more
wiley   +1 more source

MARKETS IN CRYPTO-ASSETS AND CAPITAL MARKET [PDF]

open access: yesChallenges of the Knowledge Society
Crypto-assets are defined as digital representations of value or of rights, applications of distributed ledger technology (DLT), including blockchain technology. DLT means an information repository that keeps records of transactions and that repository
Cristian GHEORGHE
doaj  

Digital Investment Toolkit: Improving the Conceptual Framework

open access: yesФинансы: теория и практика
The article develops the issues of application in investment practice of a number of official terms related to the turnover of digital financial assets as a subject of research.
A. I. Goncharov   +2 more
doaj   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

open access: yesAdvanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong   +14 more
wiley   +1 more source

Making sense of assets: Community asset mapping and related approaches for cultivating capacities [PDF]

open access: yes, 2016
This working paper critically reviews some main aspects from asset based approaches highlights key strengths and weaknesses for future research/development.
Alevizou, Giota   +2 more
core  

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