Results 131 to 140 of about 5,255,523 (302)

[Digital] Archive [PDF]

open access: yes, 2014
The study of what is collectively labeled New Media —the cultural and artistic practices made possible by digital technology—has become one of the most vibrant areas of scholarly activity and is rapidly turning into an established academic field, with ...
Harris, Katherine D
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis

open access: yesCardiovascular Diabetology
Background Insulin resistance (IR) is linked to an increased risk of frailty, yet it remains unclear whether the non-insulin-based IR indicators are associated with frailty trajectories and physical function decline.
Hui Tian   +4 more
doaj   +1 more source

Advances in the research on myokine-driven regulation of bone metabolism

open access: yesHeliyon
The traditional view posits that bones and muscles interact primarily through mechanical coupling. However, recent studies have revealed that myokines, proteins secreted by skeletal muscle cells, play a crucial role in the regulation of bone metabolism ...
MingHong Shao   +5 more
doaj   +1 more source

The impact of digital technology on design students; the changing learning journey and the emergence of a learner interface [PDF]

open access: yes, 2014
The session reflects on the research conducted in the investigation of fashion design students’ learner journey and the pedagogical impact of digital technologies on their research behaviour.
Allen, Claire, Evans, Claire
core  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Digital First

open access: yes, 2018
Kamran Ullah studeerde bestuurskunde in Leiden en was bestuurslid van de B.I.L. in 2003-2004. Na zijn studie werkt hij in diverse functies binnen de mediawereld, onder andere als presentator en eindredacteur op Radio 1. Op dit moment is hij News Content Director video bij De Telegraaf. Daarnaast is hij werkzaam als gespreksleider en trainer.
openaire   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

The Digital First-Mover

open access: yes
In an era of rapid technological disruption, traditional academic frameworks are increasingly misaligned with the global digital economy. "The Digital First-Mover" explores the psychological and economic shift toward skills-based education for the next generation.
openaire   +2 more sources

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