Results 101 to 110 of about 1,195,325 (262)

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

Grounding digital mental health and wellbeing platform development in a theory of change: a convergent mixed methods approach

open access: yesFrontiers in Psychiatry
BackgroundMental health concerns among children and young people are rising, yet only a fraction receive the care they need. Digital mental health solutions can help bridge this gap, and recent years have seen a rapid proliferation of mental health ...
Emily P. Cowling   +12 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi   +8 more
wiley   +1 more source

Child and adolescent health in the digital age

open access: yesThe Lancet: Digital Health, 2020
The Lancet Digital Health
doaj   +1 more source

Brain-movement relationship during upper-limb functional movements in chronic post-stroke patients

open access: yesJournal of NeuroEngineering and Rehabilitation
Background Following a stroke, brain activation reorganisation, movement compensatory strategies, motor performance and their evolution through rehabilitation are matters of importance for clinicians.
C. O. Muller   +10 more
doaj   +1 more source

Digital Health: General Concepts and Terminology

open access: yes
Healthcare changed tremendously over the past decades due to the availability and use of technical innovations. The technical support options for diagnosing and managing patients increase by the day and are partly driven by several factors, including the availability of good Internet connection in most Western European regions, storage of all medical ...
Bouwes, Wieke, Metting, Esther
openaire   +2 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Decision support systems for antibiotic prescription in hospitals: a survey with hospital managers on factors for implementation

open access: yesBMC Medical Informatics and Decision Making
Background Inappropriate antimicrobial use, such as antibiotic intake in viral infections, incorrect dosing and incorrect dosing cycles, has been shown to be an important determinant of the emergence of antimicrobial resistance.
Pinar Tokgöz   +3 more
doaj   +1 more source

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