Results 191 to 200 of about 12,697,710 (368)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Decision support systems for antibiotic prescription in hospitals: a survey with hospital managers on factors for implementation

BMC Medical Informatics and Decision Making
Background Inappropriate antimicrobial use, such as antibiotic intake in viral infections, incorrect dosing and incorrect dosing cycles, has been shown to be an important determinant of the emergence of antimicrobial resistance.
Pinar Tokgöz, Stephan Krayter, Jessica Hafner, Christoph Dockweiler   +3 more
doaj   +1 more source

Proactive Identification and Digital Mental Health Intervention for the Treatment of Depression Among Individuals With Likely Incurable Cancer: A Pilot Randomized Clinical Trial [PDF]

Evan M. Graboyes, Olivia Levins, Reid DeMass, Nivetha Baskar, Noelle Natale, Katherine R. Sterba, Jihad S. Obeid, Shivani Sharma, Elizabeth G. Hill, Jennifer Dahne   +9 more
openalex   +1 more source

A digital health platform for assisting the diagnosis and monitoring of COVID-19 progression: An adjuvant approach for augmenting the antiviral response and mitigating the immune-mediated target organ damage

, 2021
Yuval Ishay, Assaf Potruch, Asaf Schwartz, Marc Berg, Khurram Jamil, Samuel Agus, Yaron Ilan   +6 more
openalex   +1 more source

Sociodemographic determinants of digital health literacy: A systematic review and meta-analysis

Int. J. Medical Informatics, 2023
Marta Estrela, Guilherme Semedo, F. Roque, P. Ferreira, M. T. Herdeiro   +4 more
semanticscholar   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

Optimizing Digital Health Tools for Colorectal Cancer Screening Uptake in Federally Qualified Healthcare Centers: Insights From the Consolidated Framework for Implementation Research and Technology Acceptance Model [PDF]

Aldenise Ewing, Dede Teteh, Portia Zaire, Nicolas Nelson, Subhankar Chakraborty, Cathy Meade, Clement K. Gwede   +6 more
openalex   +1 more source

Additional file 4 of Contextualizing critical thinking about health using digital technology in secondary schools in Kenya: a qualitative analysis

, 2022
Faith Chesire, Marlyn Ochieng, Michael Mugisha, Ronald Ssenyonga, Matt Oxman, Allen Nsangi, Daniel Semakula, Laetitia Nyirazinyoye, Simon Lewin, Nelson K. Sewankambo, Margaret Kaseje, Andrew D Oxman, Sarah Rosenbaum   +12 more
openalex   +1 more source