Results 141 to 150 of about 3,006,454 (408)

Ouvrir la boîte à outils de la recherche numérique

open access: yesTic & Société, 2019
Digital methods in humanities and social sciences are often presented as disruptive towards existing methods. On the opposite, Noortje Marres claims that online methods are « redistributed » in order to apply to the digital medium.
Jean-Christophe Plantin   +1 more
doaj   +1 more source

Exploring manuscripts: sharing ancient wisdoms across the semantic web [PDF]

open access: yes, 2012
Recent work in digital humanities has seen researchers in-creasingly producing online editions of texts and manuscripts, particularly in adoption of the TEI XML format for online publishing.
Hedges, Mark   +3 more
core   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Queer Digital Humanities

open access: yes, 2022
<p>A chapter in the <em>Bloomsbury Handbook to the Digital Humanities</em> (Bloomsbury Academic, 2022) describing queer appraoches to the digital humanities.</p>
Bo Ruberg, Jason Boyd
openaire   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Citizen Humanities as a Fusion of Digital and Public Humanities?

open access: yesmagazén, 2020
Digital and public humanities have gained a foothold in academia, but very little is known about citizen humanities, which is referring to the engagement of the general public in scholarly research.
Heinisch, Barbara
doaj   +1 more source

Effective Use of Human Computer Interaction in Digital Academic Supportive Devices [PDF]

open access: yesInternational Journal of Science and Research, 3(6), 388-392 (2014), 2015
In this research, a literature in human-computer interaction is reviewed and the technology aspect of human computer interaction related with digital academic supportive devices is also analyzed. According to all these concerns, recommendations to design good human-computer digital academic supportive devices are analyzed and proposed.
arxiv  

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

A fragment-based approach for computing the long-term visual evolution of historical maps

open access: yesHumanities & Social Sciences Communications
Cartography, as a strategic technology, is a historical marker. Maps are tightly connected to the cultural construction of the environment. The increasing availability of digital collections of historical map images provides an unprecedented opportunity ...
Remi Petitpierre   +3 more
doaj   +1 more source

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