Results 191 to 200 of about 3,006,454 (408)
Longitudinal Trajectories of Digital Cognitive Biomarkers for Multiple Sclerosis
ABSTRACT Background Cognitive impairment is one of the most common and debilitating symptoms of relapsing–remitting multiple sclerosis (RRMS). Digital cognitive biomarkers require less time and resources and are rapidly gaining popularity in clinical settings.
Yi Chao Foong+17 more
wiley +1 more source
Digital twins of the Earth with and for humans
Abstract Digital twins of the Earth are digital representations of the Earth system, spanning scales and domains. Their purpose is to monitor, forecast and assess the Earth system and the consequences of human interventions on the Earth system. Providing users with the capability to interact with and interrogate the system, digital twins of the Earth ...
W. Hazeleger+27 more
openaire +6 more sources
Claustrum Volume Is Reduced in Multiple Sclerosis and Predicts Disability
ABSTRACT Objective The claustrum is a small, thin structure of predominantly gray matter with broad connectivity and enigmatic function. Little is known regarding the impact of claustrum pathology in multiple sclerosis (MS). Methods This study assessed whether claustrum volume was reduced in MS and whether reductions were associated with specific ...
Nicole Shelley+5 more
wiley +1 more source
Digital Twins in Biopharmaceutical Manufacturing: Review and Perspective on Human-Machine Collaborative Intelligence [PDF]
The biopharmaceutical industry is increasingly developing digital twins to digitalize and automate the manufacturing process in response to the growing market demands. However, this shift presents significant challenges for human operators, as the complexity and volume of information can overwhelm their ability to manage the process effectively.
arxiv
ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang+9 more
wiley +1 more source
Immunosuppressive Drugs in Early Systemic Sclerosis and Prevention of Damage Accrual
Objective Organ damage in patients with systemic sclerosis (SSc) in individual organs such as the lungs may be prevented by receiving immunosuppressive drugs (ISs). A new measure of global organ damage, the Scleroderma Clinical Trials Consortium Damage Index (SCTC‐DI), has allowed us to investigate whether receiving ISs may reduce global organ damage ...
Murray Baron+29 more
wiley +1 more source
Preventive Effect of Metformin in Radiation‐Induced Xerostomia
Head and neck cancer patients who received radiotherapy complain of severe dry mouth due to damage to the salivary glands. Metformin is an antidiabetic drug, but its radio‐protective effect has been reported. It is confirmed that metformin protects the salivary glands from radiation and provides evidence for the use of metformin in cancer treatment in ...
Sungryeal Kim+5 more
wiley +1 more source
Introduction: Digital humanities
Over the past thirty years, a new discipline has been slowly but surely gaining ground in the humanities. It has come to be known as the digital humanities.
Teresa Ferrer Valls
doaj +1 more source