Results 91 to 100 of about 811,574 (294)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Spatiogram features to characterize pearls in paintings [PDF]

Objective characterization of jewels in paintings, especially pearls, has been a long lasting challenge for art historians. The way an artist painted pearls reflects his ability to observing nature and his knowledge of contemporary optical theory ...
Cornelis, Bruno, Daubechies, Ingrid, De Mey, Marc, Dooms, Ann, Martens, Maximiliaan, Pizurica, Aleksandra, Platisa, Ljiljana, Ruzic, Tijana, Schelkens, Peter   +8 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Study of size effect using digital image correlation

Revista IBRACON de Estruturas e Materiais
Size effect is an important issue in concrete structures bearing in mind that it can influence many aspects of analysis such as strength, brittleness and structural ductility, fracture toughness and fracture energy, among others.
A. H. A. SANTOS, R. L. S. PITANGUEIRA, G. O. RIBEIRO, R. B. CALDAS   +3 more
doaj   +1 more source

Fracture toughness testing using photogrammetry and digital image correlation

MethodsX, 2018
Digital image correlation (DIC) is an optical technique commonly used for measuring displacement fields by tracking artificially applied random speckle patterns, which can sometimes be a problem for tracking small-scale displacements. DIC is particularly
Wen Hao Kan, Carlos Albino, Daniel Dias-da-Costa, Kevin Dolman, Timothy Lucey, Xinhu Tang, Julie Cairney, Gwénaëlle Proust   +7 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Effects of Rock Texture on Digital Image Correlation

Geosciences
Digital image correlation (DIC) is a non-contact optical method that can provide high-resolution strain and displacement measurements, but its effectiveness depends on surface texture contrast.
Azemeraw Wubalem, Chiara Caselle, Battista Taboni, Gessica Umili   +3 more
doaj   +1 more source

Validation of a wide plate finite element model using digital image correlation [PDF]

To investigate the influence of global plastic deformations on girth weld defect tolerance in pipelines, a parametric finite element model has been developed. This paper provides an experimental validation of the model.
De Keyser, Karel, De Waele, Wim, Denys, Rudi, Hertelé, Stijn, Van Acker, Frederik, Verstraete, Matthias   +5 more
core  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

D2IC: A differentiable 2D digital image correlation framework

SoftwareX
D2IC is an open-source Python package for two-dimensional Digital Image Correlation (DIC) based on differentiable programming. It implements a global finite-element formulation: the displacement field is discretized on a quadrilateral mesh and estimated ...
Roux Emile
doaj   +1 more source