Results 121 to 130 of about 3,447,355 (412)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Digital computer processing of X-ray photos [PDF]

, 1967
Digital computers correct various distortions in medical and biological photographs. One of the principal methods of computer enhancement involves the use of a two-dimensional digital filter to modify the frequency spectrum of the picture.
Nathan, R., Selzer, R. H.
core   +1 more source

ACE16K: A 128×128 focal plane analog processor with digital I/O [PDF]

, 2002
This paper presents a new generation 128×128 focal-plane analog programmable array processor (FPAPAP), from a system level perspective, which has been manufactured in a 0.35 μm standard digital 1P-5M CMOS technology. The chip has been designed to achieve
Domínguez Castro, Rafael, Espejo Meana, Servando Carlos, Liñán Cembrano, Gustavo, Rodríguez Vázquez, Ángel Benito   +3 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Digital interactive image analysis by array processing [PDF]

An attempt is made to draw a parallel between the existing geophysical data processing service industries and the emerging earth resources data support requirements.
Jennings, J. D., Sabels, B. E.
core   +1 more source

Developing a raster detector system with the J array processing language [PDF]

, 2002
All digital copying aims to reproduce an original image as faithfully as possible under certain constraints. In the past, image processing had to be implemented in hardware for performance reasons. Here, a 100% software solution is outlined.
Jacobs, Jan
core   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Data driven discovery of cyber physical systems

Nature Communications, 2019
Discovery of hybrid dynamical models for real-world cyber-physical systems remains a challenge. This paper proposes a general framework for automating mechanistic modeling of hybrid dynamical systems from observed data with low computational complexity ...
Ye Yuan, Xiuchuan Tang, Wei Zhou, Wei Pan, Xiuting Li, Hai-Tao Zhang, Han Ding, Jorge Goncalves   +7 more
doaj   +1 more source

STUDY OF IMAGE SEGMENTATION METHODS WITH MRI IMAGES [PDF]

Journal of Mechanics of Continua and Mathematical Sciences
Digital image processing is the use of a digital computer to process digital images. Image processing transforms input images into digital form for certain operations to obtain useful information.
Mohanapriya G., Muthukumar S., Santhosh Kumar S.   +2 more
doaj   +1 more source

Digital Image Data Hiding Techniques: A Comparative Study [PDF]

ANVESA,7(2), 105-115, 2012, 2014
With the advancements in the field of digital image processing during the last decade, digital image data hiding techniques such as watermarking, Steganography have gained wide popularity. Digital image watermarking techniques hide a small amount of data into a digital image which, later can be retrieved using some specific retrieval algorithms to ...
arxiv