Results 91 to 100 of about 3,768,016 (268)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Digital Leadership and Safety Performance in Construction Projects: The Role of Employee Competence and Adaptive Leadership

open access: yesSystems
Construction projects are increasingly shaped by digital tools such as BIM, IoT-based monitoring, digital twins, and real-time project platforms, yet safety performance remains uneven because these technologies must be interpreted, coordinated, and ...
Ali Salem   +3 more
doaj   +1 more source

Digital servitization and leadership: A holistic view on required leadership traits and skills [PDF]

open access: yesJournal of Entrepreneurship, Management and Innovation
PURPOSE: Digitalization and servitization are two major developments significantly disrupting companies’ competitive landscape. The research area that combines both aspects, digital servitization, poses substantial opportunities and challenges for ...
Florian Tagscherer   +1 more
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Digital Leadership and AI Literacy Among Financial Technology Professionals: An Empirical Investigation of Relationships and Predictive Capabilities

open access: yesSoutheast Asian Business Review
This research examined the association between digital leadership capabilities and artificial intelligence literacy among fintech professionals, examining how human-centric leadership dimensions correlate with AI competency components and their ...
Jefferson Bulan, Stephen Jay Co
doaj   +1 more source

Deconstructing leadership in the post-industrial era: A comparative study of traditional leadership styles and digital leadership practices in high schools [PDF]

open access: yesEuropean Journal of STEM Education
Leadership in high schools is undergoing a transformative shift as educational institutions adapt to the digital age. This study investigates the evolution of leadership styles from traditional to digital paradigms within the context of high schools.
John Olayemi Okunlola   +1 more
doaj   +1 more source

Digital Leadership and Sustainable Competitive Advantage: Leveraging Green Absorptive Capability and Eco-Innovation in Tourism and Hospitality Businesses

open access: yesSustainability
This study explores the influence of digital leadership (DL) on sustainable competitive advantage (SCA) in tourism and hospitality businesses, focusing on green absorptive capability (GAC) and eco-innovation (EI) as mediators.
Hamada Hussein   +6 more
semanticscholar   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Digital Leadership Pioneers: Navigating Outstanding School Principals' Successes in the Evolving Educational Landscape

open access: yesInternational Journal of Learning, Teaching and Educational Research
The need for a comprehensive study on digital leadership in education, particularly in developing countries such as the Philippines, arose from a critical gap in the literature.
Philip R. Baldera   +10 more
semanticscholar   +1 more source

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