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We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
El ordenador como máquina performativa
This article aims to approach the relationship between art and technology to reach the so-called “digital literatures”. For that purpose we pretend to develop the evolution of the technical creation (drawing and writing are considered as technical ...
Laura Sánchez Gomez
doaj
Scientific Literacy in the digital age: tools, environments and resources for co-inquiry [PDF]
This paper describes some European and International projects to promote Scientific Literacy in the digital age as well as technologies, environments and resources for co-inquiry.
Achmetova, Almira +9 more
core +233 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Estudos literários digitais: projetos, métodos, ferramentas
Brief presentation of eight websites related to Digital Literary Studies. The selection is intended to be a sample of projects, methods and digital tools, including anthologies of digital literature and digital literary studies, media archaeology ...
Ministro, Bruno
doaj +1 more source
A review of digital forensics methods for JPEG file carving [PDF]
Digital forensics is an important field of cybersecurity and digital crimes investigation. It entails applying file recovery methods to analyze data from storage media and extract hidden, deleted or overwritten files.
Ahmad Khalid, Shamsul Kamal +3 more
core
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
La « dimension argumentative » plurisémiotique du livre enrichi
The case study of this paper are two enhanced books: Beauvoir, l’enquête, by Irène Frain, and Alienare, by Chloé Delaume. The rhetoric of the digital text is essential to the study of the relationship between Frain’s and Delaume’s “author’s image” and ...
Sara Amadori
doaj +1 more source
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Preparing millennials as digital citizens and socially and environmentally responsible business professionals in a socially irresponsible climate [PDF]
As of 2015, a millennial born in the 1990's became the largest population in the workplace and are still growing. Studies indicate that a millennial is tech savvy but lag in the exercise of digital responsibility.
Burgess-Wilkerson, Barbara +3 more
core +2 more sources

