Results 121 to 130 of about 14,996,800 (353)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Building an alternative social currency: Dematerialising and rematerialising digital money across media [PDF]

open access: yes, 2014
This paper reports on the user experience and design of physical and digital forms of a mixed-media local currency. We reconceive digitally mediated transactions as social interactions and report on the development of conceptual designs informed by user ...
Ferreira, J, Perry, M
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Application of Digital Image Correlation (DIC) Method for Road Material Testing

open access: yesMaterials, 2019
The theoretical part of the paper presents the framework of the digital image correlation (DIC) method as well as its advantages and limitations. The DIC technique that can be used in static and fatigue tests is a non-contact, non-interferometric optical
Jarosław Górszczyk   +2 more
semanticscholar   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Epigenetic Regulation in Mesenchymal Stem Cell Aging and Differentiation and Osteoporosis

open access: yesStem Cells International, 2020
Mesenchymal stem cells (MSCs) are a reliable source for cell-based regenerative medicine owing to their multipotency and biological functions. However, aging-induced systemic homeostasis disorders in vivo and cell culture passaging in vitro induce a ...
Ruoxi Wang   +4 more
doaj   +1 more source

Embracing the future: embedding digital repositories in the University of London [PDF]

open access: yes, 2008
Digital repositories can help Higher Education Institutions (HEIs) to develop coherent and coordinated approaches to capture, identify, store and retrieve intellectual assets such as datasets, course material and research papers.
Hoorens, S.   +2 more
core  

On the Digital Holographic Interferometry of Fibrous Material, I. Optical Properties of Polymer and Optical Fibers

open access: yes, 2012
The digital holographic interferometry (DHI) was utilized for investigating the optical properties of polymer and optical fibers. The samples investigated here were polyvinylidene fluoride (PVDF) polymer fiber and graded-index (GRIN) optical fiber.
Barakat   +31 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Evaluation of in-situ shrinkage and expansion properties of polymer composite materials for adhesive anchor systems by a novel approach based on digital image correlation [PDF]

open access: yes, 2019
The curing reaction of thermosetting resins is associated with chemical shrinkage which is overlapped with thermal expansion as a result of the exothermal enthalpy. Final material properties of the polymer are determined by this critical process.
Lichtenegger, Helga C.   +5 more
core   +1 more source

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