Results 81 to 90 of about 945,461 (308)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A DIC based technique to measure the contraction of a skeletal muscle engineered tissue [PDF]

, 2016
Tissue engineering is a multidisciplinary science based on the application of engineering approaches to biologic tissue formation. Engineered tissue internal organization represents a key aspect to increase biofunctionality before transplant and, as ...
Carosio, Silvia, DEL PRETE, Zaccaria, Faraldi, Martina, Musaro', Antonio, Pisu, Simona, Rizzuto, Emanuele   +5 more
core   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Measurement of particle shape using digital imaging techniques

Journal of Physics: Conference Series, 2005
This paper presents an investigation into the suitability of imaging based sensors to measure particle shape and the effects of shape size on measurement consistency, testing the often used assumption that imaging based particle size analysers are insensitive to changes in particle shape. The imaging system employed is introduced and the definitions of
R M Carter, Y Yan
openaire   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Digital Metrology for Nanoindentation: Synthetic Data Generator for Error Identification

Micromachines
Digital metrology enables precise, real-time measurement and data analysis using digital tools, which enhances accuracy and efficiency in manufacturing and quality control. Among key enabling technologies, Digital Twins allow continuous control, enabling
Giacomo Maculotti, Lorenzo Giorio, Gianfranco Genta, Maurizio Galetto   +3 more
doaj   +1 more source

A noncontact measurement technique for the density and thermal expansion coefficient of solid and liquid materials [PDF]

, 1996
A noncontact measurement technique for the density and the thermal expansion coefficient of refractory materials in their molten as well as solid phases is presented.
Chung, Sang K., Rhim, Won-Kyu, Thiessen, David B.   +2 more
core   +2 more sources

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu, Yuxi Gong, Weilin Xu, Xingjian Sun, Gefei Jiang, Lei Qiu, Kexin Shi, Mengxing Wu, Yinjiao Fei, Jinling Yuan, Jinyan Luo, Yurong Li, Yuandong Cao, Minhong Pan, Shu Zhou   +14 more
wiley   +1 more source

A Review of Surface Deformation and Strain Measurement Using Two-Dimensional Digital Image Correlation

Metrology and Measurement Systems, 2016
Among the full-field optical measurement methods, the Digital Image Correlation (DIC) is one of the techniques which has been given particular attention. Technically, the DIC technique refers to a non-contact strain measurement method that mathematically
Khoo Sze-Wei, Karuppanan Saravanan, Tan Ching-Seong   +2 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source