Results 131 to 140 of about 17,520 (245)

Use of a rapid digital microfluidics-powered immunoassay for assessing measles and rubella infection and immunity in outbreak settings in the Democratic Republic of the Congo. [PDF]

PLoS One, 2022
Knipes AK, Summers A, Sklavounos AA, Lamanna J, de Campos RPS, Narahari T, Dixon C, Fobel R, Ndjakani YD, Lubula L, Magazani A, Muyembe JJ, Lay Y, Pukuta E, Waku-Kouomou D, Hao L, Kayembe JK, Fobel C, Dahmer J, Lee A, Ho M, Valenzuela JGC, Rackus DG, Shih R, Seale B, Chang A, Paluku G, Rota PA, Wheeler AR, Scobie HM.   +29 more
europepmc   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Spatially Encoded Protocell Network for Non‐Cascaded Parallel Biocomputation

Advanced Science, EarlyView.
A non‐cascaded, hydrogel‐based proteinosome computational platform is developed, in which redox‐responsive proteinosomes serve as local computing units within a shared reaction–diffusion field. Reductant inputs, countered by an auxiliary glucose gradient, regulate spatially patterned proteinosome disruption, and generate population‐level boundaries ...
Shuqi Wu, Liangfei Tian
wiley   +1 more source

Orchestrating Self-Replication in Artificial Cells with Digital Microfluidics. [PDF]

Small
Zhai G, Dimitriou P, Sengel J, Wallace MI.   +3 more
europepmc   +1 more source

Recapitulating In Vivo Pharmacokinetics and Size‐Dependent Nanomedicine Delivery in a Microfluidic Platform

Advanced Science, EarlyView.
A microfluidic tumor platform integrates pharmacokinetic flow control, vascular‐like barriers, and 3D tumor spheroids to emulate in vivo drug exposure. The system reproduces dynamic concentration–time profiles and enables size‐dependent nanoparticle transport and efficacy evaluation, providing a predictive framework for assessing nanomedicine ...
Su Jeong Kang, Moon Sup Yoon, Jae Min Lee, Min Jeong Jo, Chae Eun Jin, Dae Hwan Shin   +5 more
wiley   +1 more source

Digital Microfluidics Chips for the Execution and Real-Time Monitoring of Multiple Ribozymatic Cleavage Reactions. [PDF]

ACS Omega, 2021
Davis AN, Samlali K, Kapadia JB, Perreault J, Shih SCC, Kharma N.   +5 more
europepmc   +1 more source

Controllable Cascade Aggregation Ion Programmed Nanomachines and Simple Isolation Enable Tumor‐Derived Small Extracellular Vesicles Detection for Enhanced Breast Cancer Assessment

Advanced Science, EarlyView.
This study developed a convenient, enzyme‐free detection platform based on controllable aggregation ion nanomachines. Its favorable anti‐interference capacity and high sensitivity meet the detection requirements for clinical samples processed via a simple filtration method within 10 min.
Zhihao Zhang, Zijing Liu, Xiangyue Meng, Pengjun Jiang, Jie Qu, Yu Jiang, Binxu Qiu, Jie Chen, Piaopiao Chen   +8 more
wiley   +1 more source

Recovery of phenotypically sorted cells using droplet-digital microfluidics. [PDF]

Lab Chip
Deng Z, Perry JM, Weiss M, Genth R, Autour A, Merten CA, Shih SCC.   +6 more
europepmc   +1 more source

Discrete 2D Material Programming for 3D Shaping and Morphogenesis‐Inspired 4D Bioprinting

Advanced Science, EarlyView.
Cell‐compatible discrete 2D material programming enables 2‐to‐3D shape transformation and morphogenesis‐inspired 4D bioprinting. By patterning cell‐supportive microdomains within a responsive hydrogel, the approach programs in‐plane growth to encode target metrics.
Fereshteh Family, Aneela Davuluri, Athulya Martin, Kyungsuk Yum   +3 more
wiley   +1 more source

Nucleic acid amplification tests in digital microfluidics: the promise of next-generation point-of-care diagnostics. [PDF]

Microsyst Nanoeng
Thai DA, Liu Y.
europepmc   +1 more source