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Digital microfluidic meter-on-chip
Lab on a Chip, 2020On-chip digital microfluidic flowmetry can be designed and incorporated into standard microfluidic devices for high-precision multiplexed microflow measurements.
Zecong Fang +6 more
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Democratizing Digital Microfluidics
2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), 2021As a subset of microfluidics, digital microfluidics handles fluids as small discrete entities (e.g., droplets) by actuating them individually. The choice of actuation mechanism to handle droplets has been electrowetting, especially in the form of electrowetting-on-dielectric (EWOD) developed in early 2000s.
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2014
Electromechanically driven fluid displacement over solid surfaces has significant advantages over bulk flow regimes, particularly when the fluid volume is in the form of a droplet. Voltage-induced interfacial surface tension alterations at the unbound surface of a droplet increase the droplets' wettability over a hydrophobic surface. This phenomenon is
Kailiang Wang, Henry O. Fatoyinbo
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Electromechanically driven fluid displacement over solid surfaces has significant advantages over bulk flow regimes, particularly when the fluid volume is in the form of a droplet. Voltage-induced interfacial surface tension alterations at the unbound surface of a droplet increase the droplets' wettability over a hydrophobic surface. This phenomenon is
Kailiang Wang, Henry O. Fatoyinbo
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A digital microfluidic electrochemical immunoassay
Lab Chip, 2014Digital microfluidics (DMF) has emerged as a popular format for implementing quantitative immunoassays for diagnostic biomarkers. All previous reports of such assays have relied on optical detection; here, we introduce the first digital microfluidic immunoassay relying on electrochemical detection.
Mohtashim H, Shamsi +3 more
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Velocity Saturation in Digital Microfluidics
Langmuir, 2019In digital microfluidics, discrete droplets of fluid are made to move on an open surface with no microchannels. These systems are commonly operated by application of electrical driving forces to an array of electrodes. While these driving forces are well characterized, the dissipative forces opposing droplet movement have not been as thoroughly ...
Ian Swyer, Ryan Fobel, Aaron R. Wheeler
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Digital microfluidics using soft lithography
Lab Chip, 2006Although microfluidic chips have demonstrated basic functionality for single applications, performing varied and complex experiments on a single device is still technically challenging. While many groups have implemented control software to drive the pumps, valves, and electrodes used to manipulate fluids in microfluidic devices, a new level of ...
John Paul, Urbanski +4 more
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Machine vision for digital microfluidics
Review of Scientific Instruments, 2010Machine vision is widely used in an industrial environment today. It can perform various tasks, such as inspecting and controlling production processes, that may require humanlike intelligence. The importance of imaging technology for biological research or medical diagnosis is greater than ever.
Yong-Jun, Shin, Jeong-Bong, Lee
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Let's get digital: digitizing chemical biology with microfluidics
Current Opinion in Chemical Biology, 2010Digital microfluidics (DMF) has recently emerged as a popular technology for a wide range of applications in chemical biology. In DMF, nL-mL droplets containing samples and reagents are controlled (i.e., moved, merged, mixed, and dispensed from reservoirs) by applying a series of electrical potentials to an array of electrodes coated with a hydrophobic
Mais J, Jebrail, Aaron R, Wheeler
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Graphene based digital microfluidics
2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS), 2013We demonstrated a novel electrowetting-on-dielectric (EWOD) device for digital microfluidic using a flexible, transparent, and conducting graphene electrode. We showed that a graphene electrode had a lower leakage current and a higher breakdown voltage compared to a gold electrode when they were under the same dielectric layer such as Teflon.
X. B. Tan +3 more
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Finger-triggered digital microfluidics
2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII), 2013We present finger-driven digital microfludics (DMF) to manipulate droplets based on electrowetting on dielectric (EWOD) phenomenon. Instead of using an external power supply, we use a piezoelectric energy harvesting scheme to convert mechanical energy provided by human fingers to electric voltage pulses for droplet actuation.
Cheng Peng +2 more
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